Clinical, Etiological and Neuroradiological Profile of Children Presenting with Posterior Reversible Encephalopathy Syndrome (PRES) in a Tertiary Care Center in South India. A Retrospective Study
DOI:
https://doi.org/10.65129/medical.v1i2.36Keywords:
Investigation of PRES, Management of PRES, Posterior Reversible Encephalopathy Syndrome (PRES), Prevalence, OutcomesAbstract
Posterior Reversible Encephalopathy Syndrome [PRES], is a neurological disorder that is often reversible but has long term neurological consequences. With mortality rates as high as 16%, the pathophysiology of PRES involves two primary mechanisms: vasospasm and cytotoxic edema; and it is commonly accompanied by elevated blood pressure, disturbance is cerebral autoregulation and onset of vasogenic edema. PRES includes PCA territory infarcts, venous thrombosis, demyelinating disorders, vasculitis and encephalitis. A retrospective study was conducted on children admitted between the period of December 2022 to December 2023 at the Institute of Child Health diagnosed with PRES. The data regarding clinical and neuro-radiological presentation, etiology and outcomes were assessed on 30 children who were admitted in this period. Treatment was administered based on clinical observation and varied according to associated medical condition present. PRES should be considered in differential diagnosis in children with complaints of seizures, headache and altered mental states.
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