A Study on Clinical Profile and Outcome of Intracranial Cavernoma Patients in Tertiary Care Hospital
DOI:
https://doi.org/10.65129/surgical.v1i3.127Keywords:
Cavernoma, Hemorrhage, Seizures, ExcisionAbstract
Aim: Intracranial cavernous malformations are congenital benign hamartomas of the brain. They are more common than generally suspected. They are low flow, low pressure lesions, and their hemorrhage typically displaces and compresses adjacent tissue rather than destroying it. The clinical picture is a result of the hemorrhage in relation to the location and volume of the hemorrhage. We retrospectively reviewed our cases with Intracranial Cavernomas and presented our results. Methods: A retrospective analysis of 17 patients with Intracranial cavernous malformations admitted at Institute of Neurosurgery, RGGGH, over a period of 4 years from 2021 till now. The data was obtained from review of medical records and available imaging studies. Results: After studying the 17 intracranial cavernoma patients, we found that 12 presented with seizures, 14 of them were supratentorial, 1 was in brainstem. All underwent microsurgical excision and 15 of them improved without deficit. Conclusion: In this paper, we evaluated the demographic features, location, clinical features, surgical technique and postoperative follow up of intracranial cavernomas. Microsurgical excision is the gold standard treatment of cerebral cavernous malformations.
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References
1. Youmans JR, Winn HR. Youmans neurological surgery. 8th ed. Philadelphia: Elsevier; 2022.
2. Zabramski JM, Wascher TM, Spetzler RF, et al. The natural history of familial cavernous malformations: results of an ongoing study. J Neurosurg. 1994; 80(3):422-32.https://doi.org/10.3171/jns.1994.80.3.0422 PMID: 8113854.
3. Mouchtouris N, Chalouhi N, Chitale A, Starke RM, Tjoumakaris SI, Rosenwasser RH, et al. Management of cerebral cavernous malformations: from diagnosis to treatment. Sci World J. 2015; 2015:808314. https://doi.org/10.1155/2015/808314 PMID: 25629087 PMCID: PMC4300037.
4. Khallaf M, Abdelrahman M. Supratentorial cavernoma and epilepsy: experience with 23 cases and literature review. Surg Neurol Int. 2019; 10:117. https://doi.org/10.25259/ SNI-178-2019 PMID: 31528453 PMCID: PMC6744744.
5. Wang CC, Liu A, Zhang JT, Sun B, Zhao YL. Surgical management of brainstem cavernous malformations: report of 137 cases. Surg Neurol. 2003; 59(6):444-54. https://doi.org/10.1016/S0090-3019(03)00187-3 PMID: 12826334
6. Kondziolka D, Lunsford LD, Kestle JRW. The natural history of cerebral cavernous malformations. J Neurosurg. 1995; 83(5):8204. https://doi.org/10.3171/jns.1995.83.5.0820 PMID: 7472549.
7. Chalouhi N, Dumont AS, Randazzo C, et al. Management of incidentally discovered intracranial vascular abnormalities. Neurosurg Focus. 2011; 31(6):E1. https:// doi.org/10.3171/2011.9.FOCUS11200 PMID: 22133178.
8. D’Angelo VA, De Bonis C, Amoroso R, Cali A, D’Agruma L, Guarnieri V, et al. Supratentorial cerebral cavernous malformations: clinical, surgical, and genetic involvement. Neurosurg Focus. 2006; 21(1):E9. https://doi.org/10.3171/ foc.2006.21.1.10 PMID: 16859262.
9. Englot DJ, Han SJ, Lawton MT, Chang EF. Predictors of seizure freedom in the surgical treatment of supratentorial cavernous malformations. J Neurosurg. 2011; 115:1169-74. https://doi.org/10.3171/2011.7.JNS11536 PMID: 21819194.
10. Ferroli P, Casazza M, Marras C, Mendola C, Franzini A, Broggi G, et al. Cerebral cavernomas and seizures: a retrospective study on 163 patients who underwent pure lesionectomy. Neurol Sci. 2006; 26:390-4. https://doi.org/10.1007/s10072-006-0521-2 PMID: 16601930.
