Sternal metastasis in a case of carcinoma endometrium - Diagnostic dilemma.

Abstract

Carcinoma endometrium rarely presents with metastasis to bone and endometrial primary is rarely thought of in case of bone metastasis from a carcinoma. Available literature review suggests that this presentation is quiet unusual in carcino-ma endometrium. Here we share our experience of a woman presenting with a swelling arising from sternum which on evaluation was found to be metastasis from endometrial primary.
Cervical carcinoma is the most common gynae-cologic malignancy in India affecting pre and per-imenopausal women whereas carcinoma endo-metrium is generally seen in postmenopausal women. Presenting symptom is usually vaginal bleeding (∼90%) and most of the patients are at early stage (∼73%) and the disease is limited to the uterus at initial diagnosis [1].

Metastasis of the endometrial adenocarcinoma is in descending order to the lymph nodes, lung and the liver. Metastasis to the bone is very rare and thought to be arising from blood borne dissemina-tion of cancer cells. Bone metastases from un-known primary at presentation later found to be of endometrial adenocarcinoma origin is an even rarer presentation. We present this case here be-cause of rarity of its presentation.