STAGE 4 RETINOBLASTOMA IN A 13 YEAR OLD GIRL A CASE REPORT

Abstract

Introduction-Retinoblastoma is rare after 3 years of age, the
mean age of diagnosis being18 months in bilateral
retinoblastoma and 24 months in unilateral cases. We report
a 13 year old girl with unilateral retinoblastoma and
intracranial extension. Case History- The girl presented with
loss of vision in the left eye and prominence of the left eye
along with pain for 2 months duration. Clinical examination of
the left eye revealed no perception of light, proptosis,
shallow anterior chamber, neovascular glaucoma and total
cataract. A review of imaging done 10 months prior to
presentation showed a heterogenous intraocular mass
partially filling the globe with no optic nerve involvement.
Amore recent Imaging showed the tumour completely filling
the globe with optic nerve involvementupto the chiasm. The
differential diagnoses included optic nerve glioma and
meningioma withintraocular involvement, retinoblastoma with
intracranial extension and an intraocular inflammation with
extension. The eye was enucleated and histopathological
examination showed malignant round cell tumour consistent
with retinoblastoma. Conclusion-The differential diagnoses
and relevant literature review of an intraocular tumour with
intracranial involvement is discussed. Although rare,
retinoblastoma should be considered as a differential
diagnosis for an intraocular tumour with wide spread
involvement in a teenager