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Uterine Lymphoma - A case report

AGALYA ANGELINA S

Abstract


Extra nodal type of Non Hodgkins lymphoma  occurring in female genital tract is rare. The diagnosis is   challenging. We report a case of primary extra nodal NHL of stage IIAE according to Ann Arbor staging. A sixty three year postmenopausal unmarried lady, presented with pressure symptoms of the bladder . On evaluation, she was found to have a large cervical mass extending into the uterine cavity. Imaging, cervical biopsy and immuno histochemistry of the cervical lesion was suggestive of Double hit high grade diffuse large B cell lymphoma (DHL-DLBCL). Double hit  lymphomas do not have a favourable prognosis. She was treated with five cycles of R-CHOP regimen (rituximab, cyclophosphamide, hydroxydaunorubicin, vincristine, prednisone). She was in good condition but expired after five cycles of chemotherapy, probably due to myocardial  infarction.

 


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