comparative study of volumetric changes in body parameters and in respiratory system using computerized spirometer in teenage girls before and after menstruation

Abstract

ABSTRACTBackgroundMenstruation is a
cyclic event with endometrial sloughing
and shedding due to the effect of hormones
produced by the hypothalamo pituitary
ovarian axis (also termed as the HPO
axis). From the hypothalamus GnRH is released
in pulses, to the anterior pituitary,
stimulating the gonadotrophs, which inturn
synthesize, store and secrete gonadotropins
FSH and LH and stimulate the gonads
to synthesize and secrete sex steroids.
Aim The aim of this study is to compare
and find out the variations in body
weight, heart rate, respiratory rate, blood
pressure and the volumetric changes in
the respiratory system pre and post menstrually
in teenage girls. Methods The test
was performed using computerized spirometry
in two different phases of the menstrual
cycle the follicular phase(FP) and
the luteal phase(LP). The study variables
were weight(Wt),heart rate(HR),respiratory
rate(RR),blood pressure(BP), forced expiratory
volume(FEV1),forced vital
capacity( FVC) and forced expiratory volume
(FEV1FVC) values. The details on
the menstrual history of the subject for its
regularity were collected. Those with
regular cycles were examined and the
body parameters and the flow volume
curve using computerised spirometry was
obtained in the late luteal phase and in
the early proliferative phase during the
premenstrual and in the postmenstrual
phases.Results The results were compared
for body parameters, FVC, FEV1,
(FEV1FVC) between the premenstrual
and the post menstrual values. The mean
body weight value obtained in the premenstrual
period was 58.977.85 and the
value in the postmenstrual period was
56.286.46.This difference is considered to
be statistically significant. The differences
in body weight, HR, RR, BP, FEV1, FVC,
FEV1FVC were found to be significant
with the p-value 0.05. Conclusion This
study showed that in the luteal phase, the
respiratory effort was high and FEV1
showed better values and is due to progesterone
which produces a reflex hypoxic
drive.