A case report of false positive Bence Jones proteinuria.

Abstract

With only rare exceptions,Bence-Jones
proteinuria reflects a malignant condition.
BJP occurs frequently in patients with Multiple
myeloma. It is a plasma cell dyscrasia
characterised by monoclonal proliferation
of B cells. When there is excess production
of antibodies light chains production
exceeds heavy chain production and the
excess light chains get excreted resulting
in positive Bence Jones proteinuria. Monoclonal
production of antibodies causes a
discrete, intense band in the gamma region
called as M band, the hallmark for the
diagnosis of multiple myeloma. Though
Bence Jones proteinuria is not a prerequisite
for the diagnosis of multiple myeloma,
positive bence jones proteinuria points towards
the diagnosis of multiple myeloma.
Here we report a false positive case of
bence jones proteinuria normal Electrophoresis
pattern.