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AN UNUSUAL CASE OF AUTOIMMUNE THYROIDITIS PRESENTING WITH HYPERSOMNIA

DEEPA VS SUBRAMONIOM

Abstract


Autoimmune Thyroiditis is a chronic inflammatory disorder of the Thyroid gland. It is caused by the abnormal blood antibodies and white blood cell that damage the normal thyroid cells. It may destroy the thyroid gland, causing thyroid hormone deficiency (hypothyroidism). Diagnosis of Autoimmune Thyroiditis is difficult. This disease can occur at any age, but is most often seen in middle-aged women. It may also be associated with other autoimmune endocrine disorders. This disorder mostly incident in women. This paper reports a case of a 30 year old male with history of hypersomnia for past three months. He had no other associated complaints. TFT revealed a raised TSH, low T3 T4 (Hypothyroidism) with increased thyroid specific antibody. The patient was started on L-Thyroxine to which he responded well and became euthyroid after three months.

 


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References


Weetman AP, Mcgregor AM. Autoimmune Thyroid disease: further developments in our understanding. Endocrinol Rev 1994;15:788-830.

Noel RR, Raphael B, Burek CL. Iodine: an environmental trigger of thyroiditis. Autoimmune Rev 2002;1:97-103.

Nystrom E, Bengtsson C, Lapidus L, Petersen K, Lindsted G. Smoking A risk factor for hypothyroidism. J Endocrinol Invest 1993;16:129-31.

Gordin A, Maatela J, Miettinen A, Helenius T, Lamberg BA. Serum thyrotrophin and circulating thyroglobulin and thyroid microsomal antibodies in Finnish population. Acta Endocrinol 1979;90:33-42.

Shinno H, Inami Y, Inagaki T, Kawamukai T, Utani E, Nakamura Y et al. Successful treatment with levothyroxine for idiopathic hypersomnia patients with subclinical hypothyroidism. Gen Hosp Psychiatry 2009;31:190-3.

Hanafusa T, Borrell RP, Chiovato L, Russel RC, Doniach D, Bottazzo GF. Aberrant expression of HLA-DR antigen on thyrocytes in Grave’s disease: relevance for autoimmunity. Lancet 1983;2:1111-5.

Huber G, Staub JJ, Meier C. Prospective study of the spontaneous course of sub-clinical hypothyroidism: Prognostic value of thyrotropin, thyroid reserve and thyroid antibodies. J Clin Endocrinol Metab 2002;87:3221-6.


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