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An Unusal Case Of Cardiomyopathy Due To Hypothyroid

Chandra Shekar M, Prince Sreekumar Pius, .

Abstract


Most patients with dilated cardiomyopathy have a poor prognosis and irreversible myocardial                          dysfunction .Rarely, a reversible metabolic etiology that is amenable to specific therapy is identified. Thyroid                  dysfunction reflects the effects of hormones on calcium activated ATPase & Phospholamban and various other ion          channels.Phospholamban inactivates SERCA and helps myocardium contractility. When phospholamban is affected contractility decreases.


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References


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