SOFT TISSUE SARCOMA RETROSPECTIVE ANALYSIS
Abstract
Soft Tissue Sarcomas (STS) represent a group of rare tumors,
histopathologically diverse group of neoplasm arising from mesenchymal cells including adipose,
muscle, and connective tissues. The standard treatment of sarcomas in the localized stage is local
excision and radiotherapy. Radiotherapy may be delivered either preoperatively, by brachytherapy
after intra-operative placement of needles and post-operatively. Results - From August 2012 and
December 2013, 85 patients with primary soft tissue sarcoma were seen in Radiotherapy Unit 1.
Majority of our patients were above the age of 30 years. The incidence among males was 70. STS
predominantly was found in lower extremities (51.1 in lower limb, 16.4 in upper limb). Among the
patients treated with surgery most of them had wide local excision. Adjuvant radiotherapy was
received by 61 patients. Palliative radiotherapy was received by 2 patients for brain and vertebral
metastasis. The follow up period ranged from 6- 24 months. Out of 64 patients, no evidence of
disease was seen in 34 patients, local recurrence in 1 patient who was treated with surgery alone and
distant metastases in 9 patients. Twenty patients were lost to follow up. Conclusion - Multimodality
local therapy in the form of surgery and radiation is often necessary to local control, limb preservation,
and functional outcome in these patients. In select circumstances, adjuvant chemotherapy may
augment disease control.
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