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PRIMARY PLEURAL BENIGN MYXOID SCHWANNOMA

RAMANATHAN p

Abstract


Pleural schwannomas are exceedingly
rare neoplasms of the thoracic cavity. To
the best of our knowledge, less than 20
cases have been reported in the medical
English literature. Herein, we report the
case of primary pleural benign myxoid
schwannoma in an 55-year-old female.
The patient was originally referred to our
tertiary care hospital for further management
of right intrathoracic mass. Physical
examination and all laboratory tests were
normal. Contrast-enhanced computed
tomography scan showed a 10 cm, heterogeneous
noncalcified mass involving
the right hemithorax region. There was
no pleural effusion, ascites, or lymphadenopathy.
No pelvic masses were identified.
Patient was scheduled for surgical
resection. On thorocotomy, the mass
was interestingly found inside the thorax
attached to the pleura, and resected successfully.
A final histopathological diagnosis
of primary pleural benign myxoid
schwannoma was established. At a postoperative
6-month followup, there was no
radiological evidence of
tumor recurrence. Furthermore, literature
review on pleural schwannomas is also
prsented.


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References


J. H. McClenathan and R. J. Bloom,

“Peripheral tumors of the intercostal

nerves,” Annals of Thoracic Surgery,

vol. 78, no. 2, pp. 713–714, 2004.

S. Hu, Y. Chen, Y. Wang, K. M. Chen,

and Q. Song, “Clinical and CT manifestation

of pleural schwannoma,” Acta Radiologica,

vol. 53, no. 10, pp. 1137–

, 2012.

M. J. Kransdorf, “Benign soft-tissue

tumors in a large referral population: distribution

of specific diagnoses by age,

sex, and location,” American Journal of

Roentgenology, vol. 164, no. 2, pp. 395

–402, 1995.

K. Athanassiadi, G. Kalavrouziotis,

D. Rondogianni, A. Loutsidis,

A. Hatzimichalis, and I. Bellenis,

“Primary chest wall tumors: early

and long-term results of surgical

treatment,” European Journal of

Cardio-thoracic Surgery, vol. 19, no.

, pp. 589–593, 2001.

A. Abbas, H. Jones, G. T. Kingston,

and A. Zurek, “Malignant peripheral

nerve sheath tumour presenting

as a pneumothorax,” British

Journal of Radiology, vol. 84, no.

, pp. e197–e199, 2011.

C. Paranjape, S. R. Johnson, K.

Khwaja, H. Goldman, J. B. Kruskal,

and D. W. Hanto, “Clinical characteristics,

treatment, and outcome of

pancreatic schwannomas,” Journal

of Gastrointestinal Surgery, vol. 8,

no. 6, pp. 706–712, 2004.

F. Di Benedetto, M. Spaggiari, N.

De Ruvo et al., “Pancreatic schwannoma

of the body involving the

splenic vein: case report and review

of the literature,” European Journal

of Surgical Oncology, vol. 33, no. 7,

pp. 926–928, 2007.

V. A. Kinhal, T. H. Ravishankar,

A. I. Melapure, G. Jayaprakasha, B.

C. Range Gowda, and Manjunath,

“Pancreatic schwannoma: report of

a case and review of literature,” Indian

Journal of Surgery, vol. 72,

supplement 1, pp. 296–298, 2010.

B. A. Urban, E. K. Fishman, R. H.

Hruban, and J. L. Cameron, “CT

findings in cystic schwannoma of

the pancreas,” Journal of Computer Assisted Tomography,

vol. 16, no. 3, pp. 492–493, 1992.

S. Morbidini-Gaffney, T. E. Alpert,

G. F. Hatoum, and R. H.

Sagerman, “Benign pleural schwannoma

secondary to radiotherapy for

Hodgkin disease,” American Journal

of Clinical Oncology: Cancer Clinical

Trials, vol. 28, no. 6, pp. 640–

, 2005.

G. Gupta and A. Maniker,

“Malignant peripheral nerve sheath

tumors,” Neurosurgical Focus, vol.

, no. 6, p. E12, 2007.

K. K. Dhingra, S. Mandal, S.

Roy, and N. Khurana, “Malignant

peripheral nerve sheath tumor of

the breast: case report,” WorldJournal

of Surgical Oncology, vol. 5, article

, 2007.

P.-K. Hsu, H.-S. Hsu, H.-C. Lee

et al., “Management of primary

chest wall tumors: 14 years' clinical

experience,” Journal of the Chinese

Medical Association, vol. 69, no. 8,

pp. 377–382, 2006.

P. O'Sullivan, H. O'Dwyer, J.

Flint, P. L. Munk, and N. Muller,

“Soft tissue tumours and mass-like

lesions of the chest wall: a pictorial

review of CT and MR findings,” British

Journal of Radiology, vol. 80,

no. 955, pp. 574–580, 2007.

S.-F. Ko, T.-Y. Lee, J.-W. Lin et al.,

“Thoracic neurilemomas: an analysis

of computed tomography findings

in 36 patients,” Journal of Thoracic

Imaging, vol. 13, no. 1, pp. 21

–26, 1998.

W. K. Moon, J. G. Im, and M. C. Han,

“Malignant schwannomas of the thorax:

CT findings,” Journal of Computer Assisted

Tomography, vol. 17, no. 2, pp. 274

–276, 1993.

F. M. Enzinger and S. W. Weiss,

“Benign tumors of the peripheral nerves,”

in Soft Tissue Tumors, F. M. Enzinger,

Ed., pp. 821–828, Mosby, St Louis, Mo,

USA, 3rd edition, 1995.

S. W. Weiss, J. M. Langloss, and F. M.

Enzinger, “Value of S-100 protein in the

diagnosis of soft tissue tumors with particular

reference to benign and malignant

Schwann cell tumors,” Laboratory Investigation,

vol. 49, no. 3, pp. 299–308, 1983.

L. M. Cohen, A. M. Schwartz, and S. D.

Rockoff, “Benign schwannomas: pathologic

basis for CT inhomogeneities,”

American Journal of Roentgenology, vol.

, no. 1, pp. 141–143, 1986.

T. Moriya, W. Kimura, I. Hirai et al.,

“Pancreatic schwannoma: case report and

an updated 30-year review of the literature

yielding 47 cases,” World Journal of Gastroenterology,

vol. 18, no. 13, pp. 1538–

, 2012.


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