Cover Image

Endogenous ACTH producing lung tumor. A rare case report.

PREM ANAND J JOHN

Abstract


Mr. B , 25 year old of age,was referred
for management of his complaints, which
were suggestive of hypercortisolism. He
had features of central obesity, wrinkled
skin with recurrent skin infections,he also
reported of generalized weakness and
had uncontrolled hypertension.the dexamethasone
suppression test on him was
indicative of an endogenous ACTH producing
source (tumor) . Blood labs were
revealed elevated levels of cortisol and
acth.His MRI brain was normal with no
pituitary abnormalities. His whole body
FDG-PET scan was suggestive of a nodule
in the left upper lobe with aorticopulmonary
nodes.he underwent left upper
lobectomy,he recovered well symptomatically,
blood pressures returned to
normalcy and so as his acth and cortisol
levels.his immunohistochemistry was
suggestive of carcinoid tumour and
nodes were negative for malignancy.He
remains healthy till date..


Full Text:

PDF

References


REFERENCE:

Muller OA, von Werder K. Ectopic

production of ACTH and corticotropireleasing

hormone(CRH). J

Steroid Biochem 1992;43: 403-8.

Wajchenberg BL, Mendonca BB,

Liberman B et al. Ectopic adrenocorticotropic

hormone syndrome. End Rev

; 15: 752-87.


Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.

An Initiative of The Tamil Nadu Dr MGR Medical University