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McCune Albright syndrome is associated with patchy cutaneous pigmentation(cafe au lait spots) and fibrous dysplasia of the skeletal system. It is associated with  peripheral precocious puberty and can also cause  pituitary, thyroid and adrenal aberrations. We are reporting a five year old child who presented with knock knees, multiple cafe au lait spots and his whole body skeletal survey revealed polyostotic fibrous dysplasia.


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McCune Albright syndrome: a case report in a male; Pubmed journal Nov 2010 - by Patel KB.

Fibrous dysplasia/McCune-Albright syndrome Boyce AM, Collins MT.In: Pagon RA, Adam MP, Ardinger HH, Wallace SE, Amemiya A, Bean LJH, Bird TD, Fong CT, Mefford HC, Smith RJH, Stephens K, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2016.

McCune Albright syndrome revealed by Blaschko-linear cafe-au-lait spots on the back 2015 Feb 26. Jung AJ, Soskin S, Paris F, Lipsker Jung AJ, Soskin S, Paris F, Lipsker D. Ann Dermatol Venereol. 2015 Nov 20. pii: S0151-9638(15)01139-4. doi: 10.1016/j.annder.2015.10.585. [Epub ahead of print] French44.Nelson textbook of paediatrics- Endocrine system,chapter 556.6, page no 1891.

Nelson textbook of paediatrics-Endocrine system,chapter 556.6, page no 1891.

Atlas of Genetics and Cytogenetics in Oncology and Haematology written by Margaret Zacharin.

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