Pregnancy with Lupus Nephritis A Case report

Abstract

Systemic lupus erythematosus (SLE) is a
multisystem, auto immune , chronic inflammatory
disease of unknown etiology
with a strong predilection for young
women in the reproductive years. The
tissues and organs undergo damage mediated
by autoantibodies and immune
complexes. It is a rare condition occuring
in pregnancy with increased fetomaternal
complications. Pregnant women with
SLE have significantly greater risk of
miscarriage, spontaneous abortions, preterm
delivery, intra uterine growth retardation
, neonatal lupus, stillbirth intrauterine
fetal death, preeclampsia and
eclampsia . The incidence of renal involvement
(lupus nephritis) is same as in
the non pregnant patients. Renal flares
occur in women with active disease at
conception.Pregnancies in women with
lupus nephritis are always a high risk
situation with challenges. Due to all
these a good outcome of pregnancy in
women with lupus nephritis was a herculean
task. But now with the recent
advances and modern management the
trend has changed with a good outcome .
This paper is such a case report of a pregnant
woman with lupus nephritis who had
good fetal and maternal outcome due to
early diagnosis and effective multi disciplinary
approach .