Cover Image

IDIOPATHIC THROMBOCYTOPENIC PURPURA IN PREGNANCY-A CASE REPORT.

DEEPA LAKSHMI MUGILAN

Abstract


Thrombocytopenia in pregnancy has
many causes, including Gestatational
Thrombocytopenia, viral and bacterial
infections, and preeclampsia complicated
by haemolysis, elevated liver enzymes
and low platelet (HELLP syndrome).The
great concern for IdiopathicThrombocytopenic
Purpura (ITP) during pregnancy is
the risk of thrombocytopenia in newborn
infants. A 24 year G2P1L1 previous
lower Caesarean section presented to us
with history of gum bleeding and profuse
bleeding per vagina. She was diagnosed
of ITP in her previous pregnancy and
was treated symptomatically. In her interconception
period she was not on any
drug. In present pregnancy she was
started on steroid and transfused with 42
units of blood components .She delivered
a healthy boy baby weighed 2.250 kg by
lower segment caesarean section with
sterilization.
Her postoperative period was stormy. She
was discharged on the 21st post- operative
day. The aim of this case report to reveal
pregnancy with ITP and its clinical presentation,
investigation and management with
review of few relevant literatures.


Full Text:

PDF

References


McCrae KR, Samuels P, Schreiber

AD. Pregnancy associated thrombocytopenia:

pathogenesis and management.

Blood1992; 80: 2697-714

Crowther MA, Burrows RF, Ginsberg

J, Kelton JG. Thrombocytopenia in pregnancy:

diagnosis, pathogenesis and

management. Blood Rev 1996,

Jamaes N George, Muzahid A. Rizvi:

Thrombocytopenia: Ernest Beutler Marshall

ALichtman, Barry S Coller Thonmas

J Kipps,Uri Seligsohn: Williams Hematology:

McGraw-Hill,New York, 6 th

edition:2001. Pp 514-1520.

Giles C, Inglis TCM: Thrombocytopenia

and macrothrombocytosis in gestational

hypertension.Br J Obstet Gynaecol:

; 88:1115.

Frank Firkin, Colin Chesterman,

David Penington& Bryan Rush: de

Gruchy’s Clinical Haematology in

Medical Practice. The Hemorrhagic

Disorder: Capillary and Platelet defects;

ch14, 5thedition, Blackwell Science,

pp 377-385. Pregnancy with

Idiopathic Thrombocytopenic Purpura

- A Case Report R Akther et al.

Robert N Handin, Clotting disorders;

Harrison Principle of Medicine ;

McGraw-Hill, New York, 13th edition

, vol - 2, pp1800.

George JN, EI-Harake MA, Raskob

GE: Chronic idiopathic thrombocytopenic

purpura. N Eng J Med

;331:1207.

Lynnae millar, MD; Immune Thrombocytopenia

and Pregnancy, Last Updated:

June 29, 2006.

Keith, Edmonds: Disorders of platelets

in pregnancy: Dewhurst’s extbook

of Obstetric and Gynaecology

for post graduates; 6 th edi: Blackwell

Science Page 229-233.

Burrows RF, Kelton JG. Incidentally

detected thrombocytopenia in

healthy mothers and their infants. N

Engl J Med 1988; 319 (3):142-5

Kelton JG. Idiopathic thrombocytopenic

purpura complicating pregnancy.

Blood Rev 2002; 16 (1): 43-6.

Karim R, Sacher RA. Thrombocytopenia

in pregnancy. Curr Hematol

Rep 2004; 3 (2): 128-33.


Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.

An Initiative of The Tamil Nadu Dr MGR Medical University