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Radiation induced carcinosarcoma of the skin - a case report

VINAY V GADIGI

Abstract


Sarcoma developing within the field of
the radiation (Radiation induced sarcoma
- RIS) is a late effect of ionising radiation.
Multi-agent treatment including chemotherapy
and radiation are being increasingly
included in the treatment of cancer.
RIS is an uncommon tumour with an incidence
of less than 1 for patients with
cancer who are treated with radiation
and survive 5 years1. Little doubt exists
that the benefits of ionizing radiation far
outweigh the potential risks of developing
sarcomas. Due to paucity of experience
and literature of this rare tumor, the optimal
management is not standardized
and the role of adjuvant radiation and
chemotherapy is not defined. However
local, regional and distant recurrences
have been seen and treatment seems
best judged by the clinical presentation.
This case has been presented for its
rarity and for being the first documented
case of a carcinosarcoma arising in previously
radiated skin.


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References


Sarcoma developing within the field of

the radiation (Radiation induced sarcoma

- RIS) is a late effect of ionising radiation.

Multi-agent treatment including chemotherapy

and radiation are being increasingly

included in the treatment of cancer.

RIS is an uncommon tumour with an incidence

of less than 1 for patients with

cancer who are treated with radiation

and survive 5 years1. Little doubt exists

that the benefits of ionizing radiation far

outweigh the potential risks of developing

sarcomas. Due to paucity of experience

and literature of this rare tumor, the optimal

management is not standardized

and the role of adjuvant radiation and

chemotherapy is not defined. However

local, regional and distant recurrences

have been seen and treatment seems

best judged by the clinical presentation.

This case has been presented for its

rarity and for being the first documented

case of a carcinosarcoma arising in previously

radiated skin.

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