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Apoptosis – Journey of a Cell in Life

Dr.G.Sivakumar.MDS *,Dr.K.Shariffa.**,Dr .

Abstract


Apoptosis  is one of the key biological events  that has versatile physiological significance starting from the development of an organism, to  its differentiation, proliferation and proceeds till the last stage of  removal of defective and harmful cells. The cascade of events in               apoptosis spans through the entire cellular plethora with   morphological and functional changes occurring  in all the organelles from nucleus to the cell membrane. Apoptosis and necrosis form the two ends of a spectrum with marked           differences in their triggering factors and the sequence of cellular events.   The physiological apoptosis becomes    pathological if it gets disrupted by mutation resulting in a  variety of diseases starting from  neurodegenerative disorders to cancer . This review article emphasize the life time journey of cell


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S Leena Sankari, KMK Masthan , N Aravindha Babu, Tathagata Bhattcharjee, M Elumalai Asian Pacific J cancer prev 13(10), 4873-4878

Susan Elmore Apoptosis; A Review of Programmed Cell Death Toxicol Pathol.2007; 35(4); 495-516

Merih Onal, Gultekin Ovet and Ozkan Onal Review of Apoptosis Volume 3 Issue 1-2016

Andreas Gewies Apo Review - Introduction to Apoptosis Page 1-26.

Clemens A.SCHMITT AND SCOTT W. LOWE Apoptosis And Therapy Journal of pathology 187; 127-137(1999)

Phil Dash APOPTOSIS Basic Medical Science, St,George’s, University of London

Inna Lavrik, Alexander Golks, peter H. Krammer Journal of cell science 118, 265-267 Published by The company of Biologist 2005.

Linda E.Broker, Frank A.E.Kruyt, and Giuseppe iaccone Cell Death Independent of caspases; A Review Clin Cancer Res 2005;11(9)

Alfons Lawen Apoptosis –An Introduction BioEssays 25; 886-896 Department of Biochemistry and Molecular Biology, School of Biomedical Sciences

Rathmell, JC and Thomson,CB, (2002).Pathways of apoptosis in lymphocyte development,homeostasis,and disease.Cell 109;S97-107

Fadeel, B, Orrenius, S and Zhivotovsky, B (1999b). "Apoptosis in human disease: a new skin for the old ceremony?" Biochem Biophys Res Commun 266(3): 699-717.

Hacke, G. (2000). The morphology of apoptosis. Cell Tissue Res 301, 5–

Kerr, J. F., Wyllie, A. H., and Currie, A. R. (1972). Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26, 239–57

Majno G and Joris I. Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 146: 3_15, 1995.

Kressel M and Groscurth P. Distinction of apoptotic and necrotic cell death by in situ labelling of fragmented DNA. Cell Tissue Res 278: 549_ 556, 1994.

Rao L, Perez D, and White E. Lamin proteolysis facilitates nuclear events

during apoptosis. J Cell Biol 135: 1441_1455, 1996.

Rosenblatt J, Raff MC, and Cramer LP. An epithelial cell destined for apoptosis

signals its neighbors to extrude it by an actin- and myosin-dependent

mechanism. Curr Biol 11: 1847_1857, 2001.

Hengartner MO. Apoptosis: corralling the corpses. Cell 104: 325_328,2001.

Grimsley C and Ravichandran KS. Cues for apoptotic cell engulfment:

eat-me, don’t-eat-me and come-get-me signals. Trends Cell Biol 13: 648_656, 2003

Mashima T, Naito M, Noguchi K, Miller DK, Nicholson DW, and TsuruoT. Actin cleavage by CPP-32/apopain during the development of apoptosis.Oncogene 14: 1007_1012, 1997.

Meier, P,Finch,A and Evan, G (2000) Apoptosis in the Development.Nature 407(6805)796-801.

Zeiss, C. J. (2003). The apoptosis-necrosis continuum: insights from geneticallyaltered mice. Vet Pathol 40, 481 –95.

Prasad A, Lu M, Lukac DM, etal. An Alternative Kaposi's Sarcoma-Associated Herpesvirus Replication Program Triggered by Host Cell Apoptosis. J Virol. 2012,86(8):4404-4419.

Obregón-Henao A, Duque-Correa MA, Rojas M et al. Stable extracellular RNA fragments of Mycobacterium tuberculosis induce early apoptosis in human monocytes via a caspase-8 dependent mechanism. PLoS One. 2012, 7(1):e29970.

Toshiyuki Nakagawaa, and Junying Yuana. Activation of Caspase-12 by Calpain in Apoptosis J. Cell Biol.2000, 150 (4): 887-894.

Denis M, PengchengZhu and Judy L.GranzymeA,Induces Caspase-Independent Mitochondrial Damage, a Required First Step for Apoptosis Immunity, 2005,22(3):355- 370.

Kang YH, Yi MJ, Kim MJ,et al. Caspase-independent cell death by arsenic trioxide in human cervical cancer cells: reactive oxygen species-mediated poly(ADP-ribose) polymerase-1 activation signals apoptosis-inducing factor release from mitochondria. Cancer Res.2004, 64(24):8960-8967

Marchi S, Giorgi C, Suski JM, et al Mitochondria-Ros crosstalk in the control of cell death and aging, J signal Transduct. 2012, 1-17.

Reddy RH. Role of mitochondria in neurodegenerative diseases: mitochondria as a therapeutic target in Alzheimer's disease. CNS spectra 2009, 14(8):8-13.

Kwong JQ, Beal MF, Manfredi G. The role of mitochondria in inherited neurodegenerative diseases. J Neurochem. 2006, 97(6):1659-75.

Mariusz Karbowski. Mitochondria on guard: role of mitochondrial fusion and fission in the regulation of apoptosis. Adv Exp Med Biol. 2010, 687:131-142.

Clare Sheridan, Petrina Delivani, Sean P.Cullen.etal. Bax- or Bak-Induced Mitochondrial Fission CanUncoupled from Cytochrome c Release. Mol cell. 2008, 31(4):570-585

Jennifer R. Hom, Jennifer S. Gewandter, Limor Michael, et al. Thapsigargin inducesbiphasic fragmentation of mitochondria through calcium-mediated mitochondrial fission and apoptosis. Journal of cellular physiology, 2007, 212(2):498-508.

Susanne Herbst, Ulrich E.Schaibel, Bianca E.Schneider. Interferon Gamma Activated Macrophage by Nitric Oxide Induced Apoptosis. PLoS one, 2011, 6(5):1-8.e19105

Lebman D, Edmiston J. The Role of TGF-beta in growth, differentiation, and maturation of B lymphocytes. Microbes Infect. 1999, 1(15):1297-1304.

Singhal J, Dalasanur Nagaprashantha L, Vitsyayan R. et al. Didymin Induced Apoptosis by Inhibiting N-Myc and Up-regulating RKIP in Neuroblastoma. Cancer Prev Res(Phila) 2012,5(3):473-483.

Hung JY, Hsu YL, Ko YC.et al. Didymin, a dietary flavonoid glycoside from citrus fruits, induced Fas-mediated apoptotic pathway in human non-small-cell lung cancer cells in vitro and in vivo. Lung cancer. 2010, 63(3):366-374.

Inoue H, Waiwut P, Saiki I,et al. Gomisin N enhances TRAIL-induced apoptosis via reactive oxygen species-mediated up-regulation of death receptors 4 and 5. Int J Oncol.2012, 40(4: 1058-1065.

Zhou J, Lu GD, Ong CS, et al. Andrographolide sensitizes cancer cells to TRAILinduced apoptosis via p53-mediated death receptor 4 up-regulation. Mol Cancer Ther. 2008, 7(7):2170-2180.

Prasad S, Yadav VR, Kannappan R, et al. Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNK. J Biol Chem. 2011, 286(7):5546-5557.

Plissonnier ML, Fauconnet S, Bittard H. The Antidiabetic Drug Ciglitazone Induces High Grade Bladder Cancer Cells Apoptosis through the Up-Regulation of TRAIL. PLoS One. 2011, 6(12):1-12.

Ardehali R, Inlay MA, Ali SR, et al. Overexpression of BCL2 enhances survival of human embryonic stem cells during stress and obviates the requirement for serum factors. Proc Natl Acad Sci U S A. 2011, 22; 108(8):3282-3287.

Luo H, Zhang Y, Zhang Z, et al. The protection of MSCs from apoptosis in nerve regeneration by TGFβ1 through reducing inflammation and promoting VEGFdependent angiogenesis. Biomaterials.2012,33(17):4277-4287.

Bergmann A, Steller H.Apoptosis, stem cells, and tissue regeneration. Sci Signal. 2010, 3(145):1-16.

Ferri KF and Kroemer G. Organelle-specific initiation of cell death pathways. Nat Cell Biol 3: E255_E263, 2001.

Susanne Herbst, Ulrich E.Schaibel, Bianca E.Schneider. Interferon Gamma Activated Macrophage by Nitric Oxide Induced Apoptosis. PLoS one, 2011, 6(5):1-8.e19105

Olivares-Zavaleta N, Carmody A, Messer R, et al. Chlamydia pneumoniae inhibits activated human T lymphocyte proliferation by the induction of apoptotic and

pyroptotic pathways.J Immunol. 2011, 186(12):7120-7126.

Catarina V. Nogueira,Tullia Lindsten,Amanda M. Jamieson, et al. Rapid Pathogen- Induced Apoptosis: A Mechanism Used by Dendritic Cells to Limit Intracellular

Replication of Legionella pneumophila. PLoS Pathog. 2009, 5(6): e1000478

Ding L, Xu X, Huang Y.Transmissible gastroenteritis virus infection induces apoptosis through FasL- and mitochondria-mediated pathways. Vet Microbiol. 2012 Jan 28 online.

Wang J, Sun P, Bao Y. et al. Vitamin E renders protection to PC12 cells against oxidative damage and apoptosis induced by single-walled carbon nanotubes. Toxicology in Vitro.2012,26(1):32-41.

Han YT, Chen XH, Xie J, Zhan SM,et al. Purple Sweet Potato Pigments Scavenge ROS, Reduce p53 and Modulate Bcl-2/Bax to Inhibit Irradiation-induced Apoptosis in Murine Thymocytes. Cell Physiol Biochem. 2011, 28(5):865-872.

Jang SH, Lim JW, Morio T, etal. Lycopene inhibits Helicobacter pylori-induced ATM/ATR-dependent DNA damage response in gastric epithelial AGS cells. Free Radic Biol Med. 2012, 52(3):607-615.

Tsung-Ho Ying, Shun-Fa Yang, Su-Ju, et al. Fisetin induces apoptosis in human cervical cancer HeLa cells through ERK1/2-mediated activation of caspase-8-/caspase-3- dependent pathway. Arch toxicol. 2012,86(2):263-273.

Chen YC,Shen SC,Lee WR, etal. Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SK-HEP-1 Arch Toxicol. 2002, 76(5-6):351-359.

Wendrenmaire M, Bardou M, Peyronel C. Effects of leptin on lipopolysaccharideinduced myometrial apoptosis in an in vitro human model of chorioamnionitis. Am J Obstet Gynecol. 2011, 205(4):1-363.

Guo-Zhong Tao, Kok Sun Looi, Diana M. Toivola, etal. Keratins modulate the shape and function of hepatocyte mitochondria: a mechanism for protection from apoptosis. J Cell Sci. 2009, 122(21):3851-3855.

Armstrong J S, Steinauer K K, Hornung B, et al. Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line. Cell Death Differ, 2002, 9:252–263.

Chipuk JE, McStay GP, Bharti A,et al. Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis. Cell. 2012, 148(5):988-1000.

Kanno T, Fujita H, Muranaka S,et al. Mitochondrial swelling and cytochrome c release: sensitivity to cyclosporin A and calcium. Physiol Chem Phys Med NMR. 2002, 34(2):91- 102

. 60. Kumar S, Kain V, Sitasawad SL.High glucose-induced Ca (2+) overload and oxidative stress contribute to apoptosis of cardiac cells through mitochondrial dependent and independent pathways. Biochim Biophys Acta. 2012 Feb 28 online.

Gao G, Dou QP.N-terminal cleavage of Bax by calpain generates a potent proapoptotic 18-kDa fragment that promotes bcl-2-independent cytochrome C release and apoptotic cell death.J Cell Biochem. 2000, 80(1): 53-72.

Walter P, Ron D.The unfolded protein response: from stress pathway to homeostatic regulation. Science. 2011, 334(6059):1081 -1086

Deveraux, Q. L., and Reed, J. C. (1999). IAP family proteins —suppressors of apoptosis. Genes Dev 13, 239–52.

Livingston, D. J. (1997). In vitro and in vivo studies of ICE inhibitors. J Cell Biochem 64, 19–26.

Mocanu, M. M., Baxter, G. F., and Yellon, D. M. (2000). Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury. Br J Pharmacol 130, 197–200.

Graziani, G., and Szabo, C. (2005). Clinical perspectives of PARP inhibitors. Pharmacol Res 52, 109 –18.

Formigli, L., Papucci, L., Tani, A., Schiavone, N., Tempestini, A., Orlandini, G. E., Capaccioli, S., and Orlandini, S. Z. (2000). Aponecrosis: morphological and biochemical exploration of a syncretic process of cell death sharing apoptosis and necrosis. J Cell Physiol 182, 41–9.

Schwartz, L. M., Smith, S. W., Jones, M. E., and Osborne, B. A. (1993). Do all programmed cell deaths occur via apoptosis? Proc Natl Acad Sci USA 90, 980–4.

Noda, T., Suzuki, K., and Ohsumi, Y. (2002). Yeast autophagosomes: de novo formation of a membrane structure. Trends Cell Biol 12, 231–5.

Piacentini, M., Evangelisti, C., Mastroberardino, P. G., Nardacci, R., and Kroemer, G. (2003). Does prothymosin-alpha act as molecular switch between apoptosis and autophagy? Cell Death Differ 10, 937–9.

Meier, P,Finch,A and Evan, G (2000) Apoptosis in the Development.Nature 407(6805)796-801.


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