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A case of recurrent optic neuritis with transverse myelitis in a young boy



Recurrent optic neuritis is associated with            demyelinating disorders like multiple sclerosis or with             transverse myelitis (neuromyelitis optica) and it is important to differentiate between the two as the treatment and prognosis differ. A 13 year old boy with with recurrent bilateral optic neuritis was treated with intravenous methyl prednisolone followed by oral prednisolone for the first 2 episodes. He developed optic neuritis with transverse myelitis 3 months after the first episode. His MRI brain was normal. MRI spine was abnormal for more than 3 segments. He was treated with azathioprine and his vision improved. This case stresses the importance of the correct diagnosis and appropriate              management of bilateral recurrent optic neuritis.

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Wingerchuk DM, Hogancamp WF, O’Brien PC, Weinshenker BG. The clinical course of neuromyelitis optica (Devic’s syndrome). Neurology 1999;53:1107-14.

Wingerchuk DM, Lennon VA, Pittock SJ, Lucchinetti CF, Weinshenker BG. Revised diagnostic criteria for neuromyelitis optica. Neurology 2006;66:1485-9.

Lennon VA, Wingerchuk DM, Kryzer TJ, et al. A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet 2004;364:2106-12.

Lennon VA, Kryzer TJ, Pittock SJ, Verkman AS, Hinson SR. IgG marker of optic-spinal MS binds to the aquaporin-4 water channel. J Exp Med 2005;202:473-7.

Wingerchuk D. M., Lennon VA, Lucchinetti CF, Pittock SJ, Weinshenker BG. The spectrum of neuromyelitis optica. Lancet Neurol 2007;6:805-15.

Lana-Peixoto MA, Callegaro D. The expanded spectrum of neuromyelitis optica – evidences for a new definition. Arq Neuropsiquiatr 2012;70(10):807-13


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