Metabolic Syndrome in Adrenal Incidentaloma

Abstract

Adrenal incidentaloma is an adrenal mass that is discovered
serendipitiously during a radiological examination performed
for indications other than evaluation of adrenal disesase.
Incidentally discovered adrenal masses are mostly benign,
asymptomatic lesions often arbitrarily considered as
non-functioning tumours. Recent studies have, however,
reported that subtle cortisol production and abnormalities in
the hypothalamo-pituitary-adrenal axis are more common
than previously thought, and referred to as subclinical
Cushings syndrome. Subclinical Cushings syndrome is found
more in association with Diabetes Mellitus, Hypertension,
Obesity and Hypertriglyceridemia. The purpose of this case
study is to investigate a case of adrenal incidentaloma, its
hormonal manifestation and associated metabolic conditions,
clinical outcome and effectively manage with post-operative
follow up to evaluate the improvement in biochemical and
clinical parameters. It was concluded that Adrenal
incidentaloma should be suspected in a patient presenting
with metabolic syndrome and surgery improves metabolic
parameters.