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Angiosarcoma in chronic lymphedema a rare case of Stewart-Treves syndrome

SANJEEV KUMAR SUNDARARAJU

Abstract


The Stewart-Treves Syndrome is defined
as an angiosarcoma (very aggressive
malignant tumor originating from endothelial
cells) appearing in a specific clinical
setting. This tumor develops in patients
suffering from chronic lymphedema.
The diagnosis relies on medical
history, clinical examination and histological
assesment (biopsy or resection).
This syndrome represents a rare clinical
entity. It mostly arises from lymphedema
induced by radical mastectomy in breast
cancer patients. Unfortunately, the prognosis
is poor. A large surgical resection
is the treatment of choice, if the patient is
a candidate for surgical resection with a
curative intent. Radiotherapy is sometimes
used as a palliative local treatment.
Chemotherapy is only used in more advanced
cases, not curable by surgery
alone. We report a case of angiosarcoma
in long standing filarial lymphedematous
lower limb in a female patient.
Keyword : Angiosarcoma, chronic lymphedema,
Stewart-Treves Syndrome, filarial leg


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References


Stewart FW, Treves N: Lymphangiosarcoma

in postmastectomy lymphedema:

A report of six cases in

elephantiasis chirurgica. Cancer

:64-81, 1948

Woodward AH, Ivins JC, Soule

EH: Lymphangiosarcoma arising in

chronic lymphedematous extremities.

Cancer 30:562-572, 1972

Stewart NJ, Pritchard DJ, Nascimento

AG, et al: Lymphangiosarcoma

following mastectomy. Clin

Orthop Relat Res 320:135-141,

Angiosarcoma in a Chronically

Lymphedematous Leg: An Unusual

P e s e n t a t i o n o f S t e w a r t

T r e v e s syndrome Posted

/09/2003 Andrzej L. Komorowski,

MD, Wojciech M. Wysocki, MD,

Jerzy Mitus, MD, PHD http://

w w w . m e d s c a p e . c o m /

viewarticle/460522_1

Lymphangiosarcoma (Stewart-

Treves syndrome) in postmastect

o m y p a t i e n t s . h t t p : / /

www.jhandsurg.org/article/S0363-

(00)65102-X/abstract

Dürr HR, Pellengahr C, Nerlich

A, Baur A, Maier M, Jansson V.

Stewart-Treves syndrome as a rare

complication of a hereditary lymphedema.

Vasa. Feb 2004;33(1):42-5.

Stewart FW, Treves N. Lymphangiosarcoma

in postmastectomy lymphedema: A

report of six cases in elephantiasis chirurgica.

Cancer. 1948;1:64-81.

Hallel-Halevy D, Yerushalmi J, Grunwald

MH, Avinoach I, Halevy S. Stewart-

Treves syndrome in a patient with elephantiasis.

J Am Acad Dermatol. Aug

;41(2 Pt 2):349-50.

Offori TW, Platt CC, Stephens M, Hopkinson

GB. Angiosarcoma in congenital

hereditary lymphoedema (Milroy's disease)--

diagnostic beacons and a review

of the literature. Clin Exp Dermatol. Mar

;18(2):174-7. [Medline]


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