Malignant Mesenchymal Tumors of Maxilla: A case Series
Abstract
Introduction: Malignant Mesenchymal Tumors are
a heterogeneous group of malignancies that arise from
mesenchymal cell of origin. Management of head and neck
sarcoma remains a challenge due to rarity of cases
and lack of evidence based treatment guidelines. Maxilla
being reported as one of the common regions involved by
malignant mesenchymal tumors in the head and neck
region and they produce very few symptoms or signs while
the tumor is in its early stage. Material and Methods: In
this study the demographic, tumor, surgical and survival
parameters of all patients with a tissue diagnosis of
malignant mesenchymal tumors arising from the maxilla
between the years 2014 to 2017 were analyzed. Results:
The mean age of the study population was 38 years. Most
common presenting symptom among three patients was a
facial mass lesion. The mean duration of follow up is
12.4 months. Two patients were diagnosed with
osteosarcoma and rest of the patients were diagnosed
with leiomyosarcoma, malignant fibrous histiocytoma and
angiosarcoma each. In our study we encountered two loco
-regional recurrence and one death. Discussion: Head
and neck malignant mesenchymal tumors are a
heterogeneous group of malignancies with diverse cell of
origin and clinical presentation. Whenever feasible,
surgery is the central element in the treatment of malignant
mesenchymal tumors of head and neck region. But in view
of the anatomical constrains of the head and neck region,
achieving a R0 resection is not always possible.
Conclusion: Management of malignant mesenchymal
tumors of head and neck region continues to be a major
challenge for the multidisciplinary team due to the rarity of
cases and robust database in relation to it.
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