Retrospective analysis of clinical profile, prognostic factors and outcomes of patients with emphysematous pyelonephritis
Abstract
Aim: To study the clinical profile, prognostic factors
and outcome in patients with emphysematous
pyelonephritis (EPN). Methods: All patients admitted with
a diagnosis of EPN between the period from March 2014
to March 2017 were included in this retrospective study.
Results: Overall 64 cases were included in this study out
of which 49 were females, 15 were males. 43 (67.2%)
cases had type 2 Diabetes Mellitus. E.coli (64.1%) was the
commonest microorganism isolated in blood, urine and pus
culture. Presence of shock, DIC, increased serum
creatinine at the time of admission were identified as poor
prognostic factors. Severe hypoalbuminemia, need for
emergency dialysis and presence of polymicrobial infection
were significantly associated with failure of conservative
treatment. Conclusion: EPN requires special attention
because of its life threatening complications mainly due to
sepsis at the initial presentation, and outcome depends
upon the clinical course and prognostic factors.
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