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Surgical Intervention and Status of Oxidative Stress in Thermal Burns

Ranjith James and Nirmala Ponnambalam .

Abstract


Thermal Burns destroys cutaneous barrier and causes profound change in the system. It acts within the microcirculation and causes local and systemic changes.

The oxidative stress mechanisms are upregulated and antioxidant status are downregulated and leads to a catastrophic effect. Debridement and surgical intervention helps with the upregulation of the antioxidant status and the oxidative

stress mechanisms are downregulated helping with the considerable healing and decreasing morbidity and mortality in indicated cases.

 


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