Astrointestinal Anthrax - A rare case report
Abstract
Anthrax is an acute bacterial infection of the skin, lungs or gastrointestinal tract caused by the spore forming bacterium B. anthracis. It is a disease of herbivores and humans become infected through contact with, inhalation or ingestion of B. anthracis spores from infected animals. Gastrointestinal anthrax is an uncommon presentation of bacillus anthracis infection resulting from ingestion of undercooked meat of infected animals. This form of the disease has a fatal course as diagnosis is often difficult. Virulence of this organism is attributed to edema factor (EF), lethal factor (LF), protective antigen and anti-phagocytic factors. Gastrointestinal system (GIS) anthrax can present with predominant oropharyngeal symptoms or lower gastrointestinal symptoms. Early onset of sepsis and suppression of cell mediated immunity accounts for the high fatality rate. Prompt diagnosis with initiation of appropriate antibiotics results in better outcome. We present here the case report of a forty seven year old farmer diagnosed with gastrointestinal anthrax.
Full Text:
PDFReferences
Sternbach G. The history of anthrax. J Emerg Med. 2003 May;24(4):463–7.
Robert Koch | German bacteriologist [Internet]. Encyclopedia Britannica. [cited 2015 Aug 31]. Available from: http://www.britannica.com/biography/Robert-Koch
Bacillus anthracis [Internet]. [cited 2015 Aug 31]. Available from: http://www.ufrgs.br/imunovet/molecular_immunology/pathobacteria_anthrax.html
Kumar A, Kanungo R, Bhattacharya S, Badrinath S, Dutta TK, Swaminathan RP. Human anthrax in India: urgent need for effective prevention. J Commun Dis. 2000 Dec;32(4):240–6.
Patil RR. Anthrax: Public Health Risk in India and Socio-Environmental Determinants. Indian J Community Med Off Publ Indian Assoc Prev Soc Med. 2010 Jan;35(1):189–90.
CDC - Anthrax, Technical Information - NCZVED [Internet]. [cited 2015 Aug 31]. Available from: http://www.cdc.gov/nczved/divisions/dfbmd/diseases/anthrax/technical.html
Mwenye KS, Siziya S, Peterson D. Factors associated with human anthrax outbreak in the Chikupo and Ngandu villages of Murewa district in Mashonaland East Province, Zimbabwe. Cent Afr J Med. 1996 Nov;42(11):312–5.
Gates-Hollingsworth MA, Perry MR, Chen H, Needham J, Houghton RL, Raychaudhuri S, et al. Immunoassay for Capsular Antigen of Bacillus anthracis Enables Rapid Diagnosis in a Rabbit Model of Inhalational Anthrax. PLoS ONE [Internet]. 2015 May 5 [cited 2015 Aug 31];10(5). Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420260/
Maddah G, Abdollahi A, Katebi M. Gastrointestinal anthrax: clinical experience in 5 cases. Casp J Intern Med. 2013;4(2):672–6.
Mark E Beatty DAA. Gastrointestinal Anthrax: Review of the Literature. Arch Intern Med. 2003;163(20):2527–31.
Owen JL, Yang T, Mohamadzadeh M. New insights into gastrointestinal anthrax infection. Trends Mol Med. 2015 Mar;21(3):154–63.
Princess I, Mookkappan S, Ramesh AN, Iqbal N, Kanungo R, Vimal J, et al. Gastrointestinal anthrax in coastal south India: a critical alert on a fatal masquerader. JMM Case Rep [Internet]. 2015 Feb 1 [cited 2015 Aug 31];2(1). Available from: http://www.sgmjournals.org/content/journal/jmmcr/10.1099/jmmcr.0.000013
Sirisanthana T, Brown AE. Anthrax of the Gastrointestinal Tract. Emerg Infect Dis. 2002 Jul;8(7): 649–51.
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
An Initiative of The Tamil Nadu Dr MGR Medical University