A SUCCESSFUL MANAGEMENT OF PREGNANCY WITH LUPUS NEPHRITIS

Abstract

SLE is a multi organ auto immune disease that affects women of childbearing age. The incidence and   prevalence of SLE in pregnancy are 1.4-21.9 and 7.4-159.4  per 100,000 people,respectively.1It is first diagnosed during pregnancy in 10 -30 of the cases. Women with lupus nephritis have a good pregnancy outcome if the disease remains in remission.2 Active nephritis is associated with higher    incidence of maternal complications compared with women without nephritis.3 Fetal death with active maternal nephritis also increased than in those with quiescent nephritis. Renal involvement in SLE may either be in the form of active lupus nephritis at the time of conception, or a new onset LN or a lupus flare, all have potential maternal, perinatal morbidity and mortality. Here a case of pregnancy with active lupus nephritis of new onset had a good maternal and fetal outcome is reported.