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Buschke-Lowenstein Tumour (BLT) also known as Giant condyloma acuminatum (GCA) is a slow-growing, large, cauliflower-like tumor located in the anogenital region. This tumor has a locally destructive behavior, a high recurrence rate and occasional transformation to squamous cell               carcinoma. Risk factors include anoreceptive intercourse, HIV and immunosuppression. There is no general agreement on the choice of treatment for this tumor. Wide radical excision seems to be the best treatment, while adjuvant therapies, such as radiotherapy and immunotherapy, may achieve good results, but their effectiveness is still uncertain. We are            presenting this case for its rarity, which had a typical GCA in the perianal region along with multiple small condylomas. Such a multiple presentation is extremely rare with very few cases reported in the literature.


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Buschke A, Löwenstein L: Über karzinomähnliche Condylomata acuminata des Penis. Klin Wochenschr 1925; 4: 1726–1728.

Dawson DF, Duckworth SK, Bernhardt H, et al: Giant condyloma and verrucous carcinoma of the genital area. Arch Pathol 1965; 79: 225–231.

Trombetta U, Place RJ: Giant condyloma acuminatum of the anorectum: trends in epidemiology and management. Dis Colon Rectum 2001; 44: 1878–1886.

Creasman C, Haas PA, Fox TA Jr, Balazs M: Malignant transformation of anorectal giant condyloma acuminatum (Buschke-Löwenstein tumor). Dis Colon Rectum 1989; 32: 481–487.

Bogomoletz WV, Potet F, Molas G: Condylomata acuminate, giant condyloma acuminatum (Buschke-Löwenstein tumor) and verrucous squamous cell carcinoma of the perianal and anorectal region: a continuous precancerous spectrum? Histopathology 1985; 9: 155–169.

Batta AG, Engen DE, Reiman HM, Winkelmann RK: Intravesical condyloma acuminatum with progression to verrucous carcinoma. Urology 1990; 36: 457–464.

Chu QD, Vezeridis MP, Libbey NP, Wanebo HJ: Giant condyloma cuminatum (Buschke- Löwenstein tumor) of the anorectal and perianal regions: analysis of 42 cases. Dis Colon Rectum 1994; 37: 950–957.

Wiedemann A, Diekmann WP, Holtmann G, Kracht H. Report of a case with giant condyloma (Buschke-Lowenstein tumor) localized in the bladder. J Urol. Apr 1995;153(4):1222-4.

Dianzani C, Bucci M, Pierangeli A, Calvieri S, Degener AM. Association of human papillomavirus type 11 with carcinoma of the penis. Urology. Jun 1998;51(6):1046-8.

Papiu HS, Dumnici A, Olariu T, Onita M, Hornung E, Goldis D, et al. Perianal giant condyloma acuminatum (Buschke-Löwenstein tumor). Case report and review of the literature. Chirurgia (Bucur) . Jul-Aug 2011; 106(4):535-9.


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