Cover Image

RECURRENT MOLAR PREGNANCY- A RARE CASE REPORT

KALPANA S

Abstract


Hydatidiform moles are abnormal conception   characterised by hydropic degeneration of villi and atypical proliferation of trophoblasts. Molar pregnancies are generally sporadic and the recurrence risk increases about 2 after a single molar pregnancy and it is about 10 to 23 after two or more hydatidiform moles. Presenting an interesting case of recurrent hydatidiform mole in 4 consecutive pregnancies.

 


Full Text:

PDF

References


Lorigan PC, Sharma S, BrightN,ColemanRE, Hancock BW.Characteristics of women with recurrent molar pregnancies.GynaecolOncol 2007;78;288-92.

SebireNJ, FisherRA, FoskettM, Rees H, Sekl M, Newslands E. Risk of recurrent hydatidiform mole and

subsequent pregnancy outcome following complete or partial hydatidiform molar pregnancy.BJOG2003:110;

Michel, J. And S. Edwards. 2003. Gestational trophoblastic tumours. In: R. W.Shaw.(editor). Shaw’s text book of gynaecoiogy. 3rd ed. London: Black well Sci.,pp: 117- 123.

Berkowitz RS, IM SS, BernsteinMR,Goldstein DP. Gestational trophoblastic disease.Subsequent pregnancy outcome,including repeat molar pregnancy. J Reprod Med1998;43;81-6.

SebireNJ, Seckl MJ. Gestational trophoblastic disease: Current management of hydatidiform mole 2008;337:452-8.

Pour Reza M,Agheli N, BaghefiSB.Serumcreatinine and urea and protein level changes in hydatidiform mole JAMA 1974;230;580-1.

PalmerJR, Driscoll SG, Rosenberg L, Berkowitz RS, Lurain JR, Soper J, et al. Oral contraceptive pills in gestational trophoblastic tumours. J Natl Cancer Inst 1999; 91:635-40.

Moglabey YB, Kircheisen R, Seoudd M, El m ogharbel N, Van den VeyverI,Slim R. Genetic map maternal locus responsibie fir familial hydatidiform moles. Hum Mol Genet 1999;8:667-71

Zhao J, Moss J, Sebire NJ, Cui QC; Sekl MJ Xiang Y, Fisher RA. Analysis of the chromosomal region 19q 13.4 in two Chinese families with recurrent hydatidiform mole. Hum Reprod 2006; 21:536-41.

Berkowitz RS, Goldstein DP. Current management of gestational trophoblastic disease.Gynaecol Oncol2009;112:654-652.

Kohorn EI. Negotiating a staging and risk factor scoring system for gestational trophoblastic neoplasia J Reprod Med 2002; 47:445-450.

GoldsteinDP, Vzanten –Przybysz I, BernsteinMR,etal.Rivised FIGO staging system for gestational disease recommendations regarding therapy.JReprod Med1998;43:37-4,

Homesly HD, Blessing JA, Rettenmaier M, et al: Weekly intramuscular methotrexate for nonmetastatic gestational trophoblastic disease.Obstet Gynaecol72:413,1988.

Reubinoff BE, Lewin A, Verner M, Safran A, Schenker JG, AbeliovichD. Intracytoplasmic sperm Injection combined with periimplantation genetic diagnosis for the recurrent gestational trophoblastic disease. Hum Reprod 1997;12:805-8.

BerkowitzRS,Goldstein DP. Current management of gestational trophoblastic disease.GynaecolOncol 2009;112:654-662.


Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.

An Initiative of The Tamil Nadu Dr MGR Medical University