PRIMARY OVARIAN CARCINOID TUMOUR WITH ISOLATED TRICUSPID REGURGITATION -CASE REPORT

Abstract

Carcinoid tumours are rare slow growing
neoplasms that arise from neuroendocrine
cells. Primary ovarian carcinoid tumours
are rare, forming 0.3 percent of all carcinoid
tumours. Carcinoid heart disease due
to ovarian primary is very rare. A rare case
of primary ovarian carcinoid tumour with
isolated tricuspid regurgitation is presented.
The patient had pelvic mass and
was operated for clinical suspicion of ovarian
tumour. A large solid yellowish tumour
of size 12 cm was seen completely replacing
the right ovary. Differential diagnosis of
granulosa cell tumour and carcinoid tumour
were considered histopathologically.
Immunohistochemical study of the tumour
showed positivity for Chromogranin and
synaptophysin. No tumour was detected
elsewhere by abdominal Ultrasonograhy
and CT scan confirming the diagnosis of
primary ovarian carcinoid tumour. Post operative
review of the case details showed
isolated tricuspid regurgitation on routine
pre operative echocardiograph. The most
common cardiac manifestation of carcinoid
heart disease is tricuspid insufficiency. It is
important to be aware of carcinoid tumour
in the pathological diagnosis of ovarian
tumours, even in the absence of any clinical
indicator of carcinoid syndrome, as it
carries a better prognosis and clinical outcome
in comparison with most other malignant
ovarian tumours