Cover Image




Brown tumors are expansile osteolytic lesions of bone, occurring in hyperparathyroidism. Skeletal involvement in primary hyperparathyroidism secondary to parathyroid adenoma is very uncommon and brown tumor has become extremely a rare clinical entity. Brown tumors occur most commonly in ribs, mandible, clavicle, and pelvis, and are uncommon in the facial bones. We report a rare case of primary hyperparathyroidism presenting with brown tumor in the sphenoid sinus and the   relevant literature is reviewed.

Full Text:



Al-Gahtany M, Cusimano M, Singer W, Bilbao J, Kovacs K, Marotta T: Brown tumor of the skull base: Case report and review of the literature. J Neurosurg 98:417-420, 2003

Atabek ME, Pirgon O, Sert A, Esen HH: Extensive brown tumors caused by parathyroid adenoma in an adolescent patient. Eur J Pediatr 167:117-119, 2008

Erem C, Hacihasanoglu A, Cinel A, Ersoz HO, Reis A, Sari A, Kose M, Ukinc K, Telatar M: Sphenoid sinus brown tumor, a mass lesion of occipital bone and hypercalcemia: An unusual presentation of primary hyperparathyroidism. J Endocrinol Invest 27:366-369, 2004

Angadi PV, Rekha K, Shetty SR: An exophytic mandibular brown tumor: An unusual presentation of primary hyperparathyroidism. Oral maxillofac Surg 14: 67-69, 2010

Jebasingh F, Jacob JJ, Shah A, Paul TV, Seshadri MS: Bilateralmaxillary brown as the first presentation of primary hyperparathyroidism. Oral Maxillofac Surg 12:97-100, 2008

Jouan A, Zabraniecki L, Vincent V, Poix E, Fournie B: An unusual presentation of primary hyperparathyroidism: Severe hypercalcemia and multiple brown tumors. Joint Bone Spine 75: 209-211, 2008

Knowles NG, Simith DL, Outwater EK: MRI diagnosis of brown tumor based on magnetic susceptibility. J Magn Reson Imaging 28:759-761, 2008

Takeshita T, Tanaka H, Harasawa A, Kaminaga T, Imamura T, Furui S: Brown tumor of the sphenoid sinus in a patient with secondary hyperparathyroidism: CT and MR imaging findings. Radiat Med 22:265-268, 2004

Sahan MH, Guner S, Guner SI: Radiological finding in the primary hyperparathyroid case with multiple brown tumors; A case report. East J Med 13:30-34, 2008


  • There are currently no refbacks.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.

An Initiative of The Tamil Nadu Dr M.G.R. Medical University