University Journal of Pre and Paraclinical Sciences
CARDIOVASCULAR RESPONSES TO SUSTAINED HANDGRIP IN OBESE FEMALES
Abstract
Obesity is an independent risk
factor for cardiovascular morbidity and
mortality. High incidence of cardiac autonomic
nerve dysfunctions are noted in
obese subjects. This study was done to
assess the cardiovascular responses to
sustained handgrip in obese females. This
study included 40 obese females aged 35-
45years with BMI more than 30 Kg per m2
as study group and 40 nonobese females
in same age group with BMI between 18.5-
24.9 Kg per m2 as control. Cardiovascular
sympathetic activity was assessed by
handgrip dynamometer by recording pulse
rate and blood pressure before and after
hand grip test.Studentst test and Pearsons
correlation coefficient test were used for
statistical analysis. The results indicated a
higher level of resting pulse rate, resting
systolic and diastolic pressures in obese
as compared to control whereas the obese
females revealed a lower diastolic pressure
response for hand grip as compared
to nonobese controls. The maximum systolic
blood pressure and pulse rate during
hand grip, systolic blood pressure
difference and pulse rate difference between
rest and handgrip were not significant
between the two groups. This study
showed sympathetic nerve activity may be
reduced in obesity which may be the
cause for various cardiovascular complications.
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