Cover Image




Back ground Senile cataract is one of the
consequences of ageing. With ageing the
alteration in membrane permeability of the
lens epithelium coupled with the changes
in sodium and potassium ion levels in
aqueous humour may accentuate ionic imbalance
within the lens and progression of
cataract.Aim To compare serum sodium
and potassium ion levels in senile cataract
patients with that of normal individuals.
Materials and methods 50 males with senile
cataract were randomly selected from
the outpatient facility of department of ophthalmology,
Government Rajaji Hospital,
Madurai. 50 age matched males without
senile cataract were taken as controls.
Both cases and controls were on normal,
mixed, south Indian diet. Individuals with
secondary cataract, hypertension or diabetes,
individuals on medications and disorders
affecting serum sodium or potassium
ion levels, dehydration, edema or on salt
restricted diet were excluded from the
study. After getting written informed consent,
basal parameters were measured.
Ophthalmic evaluation of all participants
was done. Under strict aseptic precautions
2 ml of venous blood was collected
and levels of serum sodium and potassium
ions were estimated by auto analyzer
Easylyte method.Results The data
obtained was analyzed using Students t
test. Serum levels of sodium ions were
found to be higher in cases 142mEq per l
than in controls 139.5mEq per l with a significance
of less than 0.001. There was no
significant difference in the serum levels
of potassium ions in cases 4.192mEq per
l compared to controls 4.136mEq per
l.Conclusion An elevated level of serum
sodium ions may be a risk factor for progression
of senile cataract.

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