Cover Image

A COMPARISON OF COGNITIVE FUNCTIONS IN STABLE PATIENTS WITH COPD AND AGE-MATCHED HEALTHY VOLUNTEERS USING MINI-MENTAL STATE EXAMINATION QUESTIONNAIRE.

PALANI S SUBRAMANIAM

Abstract


Chronic Obstructive Pulmonary Disease
(COPD) is an airway disease characterized
by air flow limitation and is not fully
reversible. COPD is a multisystem disorder
and is a major public health problem.
Cognitive dysfunction is common and clinically
important in COPD patients. We investigated
the diagnostic accuracy of Mini
Mental State Examination (MMSE) in
screening cognitive function in 50 clinically
stable patients with COPD with mean age
of 50.12 years and 50 healthy controls with
mean age of 51.72 years. This case control
study was carried out in the Department
of Physiology, Kilpauk Medical College,
from September 2012 to August
2013. Data were analyzed by independent
samples t-test. Stable COPD patients
scored a mean of 22.34 (borderline impaired
cognitive functions) and control
group scored a mean of 25.84. The mean
MMSE score was significantly lower in stable
COPD patients. A score of 23 and
above out of 50 is considered as normal
cognitive function. In conclusion, MMSE
can be used as a screening tool to detect
cognitive dysfunction in stable COPD patients.


Full Text:

PDF

References


Antonelli-Incalzi R et al, Dement Geriatr

Cogn Disord. 2007; 23(4) :264-70.Epub

mar 12 Screening of cognitive

function in chronic obstructive pulmonary

disease. MMSE and 5-item

IADL scale can be used to exclude

cognitive dysfunctions in COPD patients.

FolsteinMF, FolsteinSE,

McHughPR (1975)”Mini-mental

state”.A practical method for grading

the cognitive state of patients for the

clinician". Journal of Psychiatric Research

(3): 189-98.

Gupta PP et al, Lung India. 2013

jan; 30(1): 5-11. A comparison of

cognitive functions in non-hypoxemic

chronic obstructive pulmonary disease

(COPD) patients and agematched

healthy volunteers using

mini-mental state examination questionnaire

and event- related potential

, P300 analysis.

Incalzil RA et al, Aging Clin Exp Res.

oct;14(5):395-401. To assess both

the prevalence and main correlates of

subclinical cognitive dysfunction in older

patients with non-hypoxemic COPD.

Incalzi RA et al, Respir Med. 1998

mar;92(3):527-33. Predicting cognitive

decline in patients with hypoxemic

COPD.

Isoaho R, Int Psychogeriatr. 1996

Spring; 8(1): 113 – 25. Chronic obstructive

pulmonary disease and cognitive impairment

in the elderly.

John J.Reilly et al,Chronic obstructive

Pulmonary Disease, Harrison”s

Principles of Internal Medicine, 18the,

p2151-60.

Mini-Mental State Examination. Psychological

Assessment Resources,

Inc." Retrieved 2006-06-22.

Salik Y et al, Arch Gerontol Geriatr.

nov-dec; 45(3)273-80.Epub 2007

mar 6. Cognitive function and its effects

on the quality of life status in the patients

with chronic obstructive pulmonary disease

(COPD).

US, Folstein MF, Folstein SE & PR

McHugh, "Mini-mental state : a practical

method for grading the cognitive state

of patients for the clinician", published

-06-08.


Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.

An Initiative of The Tamil Nadu Dr M.G.R. Medical University