A COMPARISON OF COGNITIVE FUNCTIONS IN STABLE PATIENTS WITH COPD AND AGE-MATCHED HEALTHY VOLUNTEERS USING MINI-MENTAL STATE EXAMINATION QUESTIONNAIRE.
Abstract
Chronic Obstructive Pulmonary Disease
(COPD) is an airway disease characterized
by air flow limitation and is not fully
reversible. COPD is a multisystem disorder
and is a major public health problem.
Cognitive dysfunction is common and clinically
important in COPD patients. We investigated
the diagnostic accuracy of Mini
Mental State Examination (MMSE) in
screening cognitive function in 50 clinically
stable patients with COPD with mean age
of 50.12 years and 50 healthy controls with
mean age of 51.72 years. This case control
study was carried out in the Department
of Physiology, Kilpauk Medical College,
from September 2012 to August
2013. Data were analyzed by independent
samples t-test. Stable COPD patients
scored a mean of 22.34 (borderline impaired
cognitive functions) and control
group scored a mean of 25.84. The mean
MMSE score was significantly lower in stable
COPD patients. A score of 23 and
above out of 50 is considered as normal
cognitive function. In conclusion, MMSE
can be used as a screening tool to detect
cognitive dysfunction in stable COPD patients.
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Antonelli-Incalzi R et al, Dement Geriatr
Cogn Disord. 2007; 23(4) :264-70.Epub
mar 12 Screening of cognitive
function in chronic obstructive pulmonary
disease. MMSE and 5-item
IADL scale can be used to exclude
cognitive dysfunctions in COPD patients.
FolsteinMF, FolsteinSE,
McHughPR (1975)”Mini-mental
state”.A practical method for grading
the cognitive state of patients for the
clinician". Journal of Psychiatric Research
(3): 189-98.
Gupta PP et al, Lung India. 2013
jan; 30(1): 5-11. A comparison of
cognitive functions in non-hypoxemic
chronic obstructive pulmonary disease
(COPD) patients and agematched
healthy volunteers using
mini-mental state examination questionnaire
and event- related potential
, P300 analysis.
Incalzil RA et al, Aging Clin Exp Res.
oct;14(5):395-401. To assess both
the prevalence and main correlates of
subclinical cognitive dysfunction in older
patients with non-hypoxemic COPD.
Incalzi RA et al, Respir Med. 1998
mar;92(3):527-33. Predicting cognitive
decline in patients with hypoxemic
COPD.
Isoaho R, Int Psychogeriatr. 1996
Spring; 8(1): 113 – 25. Chronic obstructive
pulmonary disease and cognitive impairment
in the elderly.
John J.Reilly et al,Chronic obstructive
Pulmonary Disease, Harrison”s
Principles of Internal Medicine, 18the,
p2151-60.
Mini-Mental State Examination. Psychological
Assessment Resources,
Inc." Retrieved 2006-06-22.
Salik Y et al, Arch Gerontol Geriatr.
nov-dec; 45(3)273-80.Epub 2007
mar 6. Cognitive function and its effects
on the quality of life status in the patients
with chronic obstructive pulmonary disease
(COPD).
US, Folstein MF, Folstein SE & PR
McHugh, "Mini-mental state : a practical
method for grading the cognitive state
of patients for the clinician", published
-06-08.
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