A COMPARATIVE STUDY OF DYNAMIC RESPIRATORY FUNCTIONS IN TERM PREGNANT WOMEN.
Abstract
In pregnancy, the enlarging uterus and the
hormonal effects alter the lung volumes
and capacities. Pulmonary function test is
an important tool to assess the respiratory
functions of an individual. Aim of the study
was to evaluate the changes in dynamic
respiratory functions in term pregnant
women and to compare parameters of
study group with that of control group. 30
adult female primi, in their third trimester
pregnancy (36- 38 weeks) selected from
the Department of Obstretics and Gynaecology,
RSRM, Stanley Medical College
Hospital were chosen after institutional
ethical committee approval. PFT was performed
using SPIROLAB II, in the sitting
posture in the morning and compared with
age matched controls chosen from the
Master Health Check-up Clinic, Stanley
Medical College Hospital. Data collected
was analyzed statistically by unpaired student
t test using SPSS version 15.0. Of the
total 30 subjects in study group, the mean
ages in years was 23.87
2.98 and mean BMI was 25.29 2.67 and
that of control group the mean ages in
years was 24.53 2.61 and mean BMI was
22.14 3.57. On comparing PFT parameters
among study and control group we
observed FVC (2.06 0.30), FEV1 (2.03
0.29), FEV1 FVC (0.98 0.02) of study
group and that of control group FVC (2.10
0.46), FEV1 (2.08 0.46) and FEV1 FVC
(0.99 0.02) there was no significant
change. PEF (4.29 1.15) among study
group when compared to that of control
group PEF (5.23 1.28) was highly significant
with P value 0.004. MVV (56.54
15.91) of study group when compared to
that of control group MVV (73.02 27.01)
was highly significant with P value 0.006.
Thus pregnancy is characterized by sequence
of dynamic physiological changes
that impact on multiple organ system
functions and is associated with various
changes in pulmonary anatomy and
physiology. Hence from this study we conclude
that assessing pulmonary function
test in third trimester pregnancy invariably
shows us significant respiratory compromise.
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