Nocardiosis-a rare clinical entity. Experience from a tertiary care centre.
Abstract
Nocardiosis is a rare infection, commonly
seen in the immunocompromised, having
diverse presentations. This was a retrospective
epidemiological analysis of 28 patients
with Nocardia spp in their clinical
samples , presenting at a tertiary hospital
in South India during the years 2012-2013.
We found that the most common predisposing
condition was corneal ulcer following
trauma to the eye, closely followed by
immunosuppressant drugs and the most
commonly obtained species was Nocardia
asteroides.
Full Text:
PDFReferences
Beaman BL, Beaman L. Nocardia
species: host-parasite relationships. Clin
Microbiol Rev. 1994 Apr;7(2):213–64.
Mandell, Douglas and Bennett -
Principles and Practice of Infectious Diseases,
th Edition.
P.I Lerner, Nocardiosis, CID http://
cid.oxfordjournals.org/
content/22/6/891.full.pdf
Saubolle MA, Sussland D. Nocardiosis
Review of Clinical and Laboratory Experience.
J
Clin Microbiol. 2003 Oct 1;41
(10):4497–501.
Garrett MA, Holmes HT, Nolte FS.
Selective buffered charcoal-yeast
extract medium for isolation of nocardiae
from mixed cultures. J Clin Microbiol.
Jul 1;30(7):1891–2.
Wilson RW, Steingrube VA, Brown
BA, Wallace RJ. Clinical Application
of PCR-Restriction Enzyme Pattern
Analysis for Rapid Identification of
Aerobic Actinomycete Isolates. J Clin
Microbiol. 1998 Jan 1;36(1):148–52.
Conville PS, Fischer SH, Cartwright
CP, Witebsky FG. Identification
of Nocardia Species by Restriction
Endonuclease Analysis of an
Amplified Portion of the 16S rRNA
Gene. J Clin Microbiol. 2000 Jan
;38(1):158–64.
Laurent FJ, Provost F, Boiron P.
Rapid Identification of Clinically RelevantNocardia
Species to Genus
Level by 16S rRNA Gene PCR. J
Clin Microbiol. 1999 Jan 1;37(1):99–
Roth A, Andrees S, Kroppenstedt
RM, Harmsen D, Mauch H. Phylogeny
of the Genus Nocardia Based on
Reassessed 16S rRNA Gene Sequences
Reveals Underspeciation
and Division of Strains Classified as
Nocardia asteroides into Three Established
Species and Two Unnamed
Taxons. J Clin Microbiol.
Feb 1;41(2):851–6.
Brown-Elliott BA, Biehle J, Conville
PS, Cohen S, Saubolle M, Sussland D,
et al. Sulfonamide resistance in isolates
of Nocardia spp. from a US multicenter
survey. J Clin Microbiol. 2012 Mar;50
(3):670–2.
Ambaye A, Kohner PC, Wollan PC,
Roberts KL, Roberts GD, Cockerill FR.
Comparison of agar dilution, broth microdilution,
disk diffusion, E-test, and
BACTEC radiometric methods for antimicrobial
susceptibility testing of clinical
isolates of the Nocardia asteroides complex.
J Clin Microbiol. 1997 Apr 1;35
(4):847–52.
Department of AIDS Control,NACO
Annual Report, 2012-2013 [Internet].
[cited 2014 Aug 11]. Available from:
h t t p : / / w w w . n a c o . g o v . i n / u p l o a d /
Publication/Annual%20Report/Annual%
report%202012-13_English.pdf
YANG M, XU M, WEI W, GAO H,
ZHANG X, ZHAO H, et al. Clinical findings
of 40 patients with nocardiosis: A
retrospective analysis in a tertiary hospital.
Exp Ther Med. 2014 Jul;8(1):25–30.
Mootsikapun P, Intarapoka B,
Liawnoraset W. Nocardiosis in Srinagarind
Hospital, Thailand: review of 70
cases from 1996–2001. Int J Infect Dis.
May;9(3):154–8.
Hakawi AM, Al Rabiah FA. Clinical
pattern of nocardiosis in Saudi Arabia: a
case series. East Mediterr Health J Rev
Santé Méditerranée Orient Al-Majallah Al
-iyah Li-Sharq Al-Mutawassi. 2008
Aug;14(4):966–71.
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
An Initiative of The Tamil Nadu Dr M.G.R. Medical University