University Journal of Pre and Paraclinical Sciences
A Study On Phenotypic Characterisation And Antimicrobial Susceptibility Pattern Of Acinetobacter Isolates From Various Clinical Samples In A Tertiary Care Hospital
Abstract
Abstract : Acinetobacter spp. have emerged as an important nosocomial pathogen,especially in intensive care settings1,2. Despite their low pathogenic potential they are being reported increasingly as the causal organism of numerous hospital outbreaks in several countries3,4 .In a recent international multicentre study,Acinetobacter spp were ranked amongst the 10 organisms most commonly causing septicaemia in 18 of 44 large European hospitals5.Different levels and patterns of antimicrobial susceptibilities have been found among different Acinetobacter species6.Several studies reported a higher occurrence of multidrug resistance in A.baumannii compared with non-A.baumannii species7,8.Intraspecies diversity of antimicrobial susceptibilities has also been reported.Hence this study was done to speciate and to determine the Antimicrobial susceptibility of Acinetobacter isolates in our Tertiary care hospital. In this study,a total of 6553 samples like blood,CSF,and other bodyfluids were analyzed.The period of study was for 3 months from August 2011-October 2011. Totally 543 non-fermenters were isolated ,out of which 100 were Acinetobacter.Speciation was done using simplified phenotypic tests,which showed A.calcoaceticusbaumanii complex(87),A.lwoffi (7),A.junii(4),A.hemolyticus(2). Resistance pattern to various drugs were cefoperazonesulbactum (11), Amikacin(43), Ofloxacin(49), Ceftazidime(55), Gentamicin(57), Chloramphenicol (93).
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