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AN INTERESTING CASE OF MALIGNANT THYMOMA - A CASE REPORT

RAJESH NATARAJ A P ARUMUGHAMPILLAI

Abstract


Primary tumors of thymus are uncommon
and accounts for less than 1percent of all
neoplasms. Thymomas and Lymphomas
are the commonest primary tumors .A
case of 45 year old male presented with
features of difficulty in breathing for the
past 7 months. Investigation revealed
lobulated heterogeneous mass in anterior
mediastinum. Guided FNAC was done and
was suggestive of Thymoma. Surgical resection
of the mass could not be done due
to invasion to adjacent organs. Histopathological
examination of biopsy showed
features of Invasive Malignant Thymoma-
Type B3 and Type A.Hence this case is
reported for its rarity by histopathological
classification.


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References


REFERENCES:

Saul Suster, Cesar A. Moran. Thymoma

Classification- Current Status and

Future Trends.ASCP 2006; 125:542-54.

Kazuya Kondo, Kiyoshi Yoshizawa, Masaru

Tsuyuguchi, Suguru Kimura, Masayuki

Sumitomo,Junji Morita, Takanori Miyoshi,

Shoji Sakiyama, Kiyoshi Mukai,

and Yasumasa Monden. WHO

Histologic Classification is a Prognostic

Indicator in Thymoma.Ann Thorac

surg2004; 77:1183-8.

Pescarmona E,Rendina EA,Venuta

F,Ricci C,Ruco LP,Baroni CD. The Prognostic

implication of thymoma histologic

subtyping. A study of 80 consecutive

cases.AJCP 1990; 93(2):190-5.

Jean E. Lewis, Mark R. Wick,ZT Bernd

W. Scheithauer, Philip E. Bernatz, and

William F. Taylor. Thymoma-A Clinicopathologic

Review. Cancer1987; 60:2727-

Jeanne M. Verley,T and karl H. Hollmann.

Thymoma- A Comparative Study

of Clinical Stages,Histologic Features,

and Survival in 200 Cases. Cancer1985;

:1074-86.

W J Curran Jr,M J Kornstein,J J

Brooks,A T Turrisi.Invasive thymoma: the

role of mediastinal irradiation following

complete or incomplete surgical resection.

ASCO1988.7.Nakahara K,Ohno K,Hashimoto J,Maeda

H,Miyoshi S,Sakurai M,Monden

Y,Kawashima Y. Thymoma: Results with

complete resection and adjuvant postoperative

irradiation in 141 consecutivepatients.

JTCS1988; 95(6):1041-47.

Giuliano Maggi, Caterina Casadio, Antonio

Cavallo, Roberto Cianci,Massimo

Molinatti, , and EnricoRuffini. Thymoma:

Results of 241 Operated Cases.Ann.Thrac

Surg1992; 52:252-6.

Rosai and Ackerman. Mediastinun,

Chapter 8 .In.Surgical Pathology. 10th ed

vol 1, Juan Rosai( Elsevier/UK)2011:443-

John K C Chan.Tumours of the lymphoreticular

system,including spleen and thymus,

Chapter 21.In. Diagnostic Histopathology

of Tumours .4t h ed

vol2,Christopher DM Fletcher. (Elsevier/

UK) 2013:1558-1602.

Robbins and cotran . Diseases of white

blood cells,Lymph nodes,spleen and Thymus,

Chapter13.In.Pathologic basis of disease.

th ed,Kumar,Abbas(Saunders Elsevier/

UK)2010:635-7

Williamr Salyer, JosephC. Ecclestom

.THYMOMA-A Clinical and Pathological

Study of 65 Cases .Cancer1976;

:229-49

William.D.Travis,Elizabeth Brambilla,

H.Konrad Muller Hermelink and Curtis

C.Harris.Tumours of Thymus,Chapter

In.WHO classification of tumours,

Pathology & Genetics,Tumours of

the Lung,Pleura,Thymus and Heart.IARC

(France)2004:145-248.

Meinoshin Okumura,Mitsunori Ohta,

Hisashi Tateyama, Katsuhiro Nakagawa,

Akihide Matsumura, Hajime Maeda,Hiroto

Tada,Tadaaki Eimoto,Hikaru Matsuda,

Akira Masaoka,

The World Health Organization Histologic

Classification System Reflects the Oncologic

Behavior of Thymoma-A Clinical

Study of 273 Patients, ACS2002; 624-32.

Leticia Quintanilla-Martinez,Earl W

Wilkins,Noah Choi,James Efird,Eugen

Hug,Nancy L Harris.Thymoma- Histologic

Subclassification Is an Independent Prognostic

Factor.Cancer 1994;74(2):606-17.

Raffaele Lattes. Thymoma and other

tumors of the thymus- An Analysis of 107

Cases.Cancer 1962; 15:1224-60.

Suster S,Moran CA.Thymoma, atypical

thymoma, and thymic carcinoma. A

novel conceptual approach to the classification

of thymic epithelial neoplasms.

AJCP1999;111(6):826-833.

Federico Venuta, Marco Anilea, Daniele

Disoa, Domenico Vitolo, Erino A.

Rendina, Tiziano De Giacomo, Federico

Francioni, Giorgio Furio Coloni. Thymoma

and thymic carcinoma.EJCTS2010; 37:13

-25.

Shahinaz M. Gadalla1, Arun Rajan,

Ruth Pfeiffer, Sigurdur Y. Kristinsson,

Magnus Bjorkholm,OlaLandgren and

Giuseppe Giaccone. A population-based

assessment of mortality and morbidity

patterns among patients with thymoma.

IJC2011; 128:2688-94.

Saul Suster, Juan Rosai.Thymic Carcinoma,

A Clinicopathologic Study of 60

Cases.Cancer 1999;67:1025-32. 21.Zhi-

Feng Mao, Xue-An Mo, Chao Qin, Yong-

Rong Lai, Maree Hackette, Incidence of Thymoma

in Myasthenia Gravis: A Systemic Review.

JCN2012;8:161

Shanda Blackmon,Richard S.Irwin.Philip

T.Cagle,Timothy C.Allen,J.D,Dina

R.Mody,Armando E.Fraire. Thymoma.

In.Atlas of Neoplastic Pulmonary Disease2010:

-117

Eric A. Engels. Epidemiology of thymoma

and associated malignancies.JTO 2010; 5

(4): 260–265.

Narendra Kumar,Ritesh Kumar,Anjan

Bera,Sushmita Ghoshal,Rakesh Kapoor,BD

Radotra,Suresh Chander Sharma.

Thymoma: Clinical experience from a tertiary

care institute from North India.

JCRT2013;9:235-9.

C. Benson, R. S. Kristeleit, S. Ashley, S.

Dolly, C. Mikropoulos, M. O'Brien and

S.Popat.

Retrospective review of all patients with thymoma

treated over the last 33 years at the

Royal Marsden Hospital.JCO2010; 28

(15):7095.

Akira Masaoka. Staging System of Thymoma.

JTO2010; 5(4):304-12. 27.Frank

C.Detterbeck and 27 Ahmad Zeeshan. Review

article, Thymoma: current diagnosis

and treatment. CMJ2013;126(11):2186-91


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