University Journal of Pre and Paraclinical Sciences
MIXED EPITHELIAL AND STROMAL TUMOUR OF THE KIDNEY - A RECENTLY RECOGNISED RARE ENTITY
Abstract
Mixed epithelial and stromal tumour
(MEST) a predominantly benign tumour of
the kidney has recently been described
and accounts for 0.2-0.28 percent of all
renal tumours. Here we report a case of
MEST in a 45 year old postmenopausal
woman. She presented with abdominal
pain and dysuria. Radiological studies revealed
a renal mass which was suspected
to be malignant. The resected kidney
showed a solid and cystic mass arising
from the lower pole of the kidney. Histologically
the tumour showed biphasic
pattern with epithelial and stromal components
and a diagnosis of MEST was made.
Immunohistochemistry showed cytokeratin
positivity in the epithelial component and
vimentin positivity in the stromal component.
There was no malignant focus. The
prognosis of these tumours is usually very
favourable. However, malignant cases
have been described. Therefore, while
dealing with cystic lesions of the kidney
this rare entity and the even rarer possibility
of malignant change should be borne in
mind.
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