A TERTIARY CARE HOSPITAL EXPERIENCE OF NON CLEAR CELL RENAL CELL CARCINOMA

Abstract

Renal cell carcinomas are a heterogenous
group of tumours with varying prognosis.
Most common histological type is clear cell
variant constituting about 60 70 of all
cases. The rest comprises a mixture of tumors
of different histological types. Hence
in this study we aimed to evaluate the clinical
and histomorphological features of non
-clear cell renal cell carcinomas. Among
renal cell carcinomas diagnosed over a
period of 6 years and two months, 40
cases (28.5) fell into the category of nonclear
cell type. They included papillary,
chromophobe, sarcomatoid, unclassified
and collecting duct carcinomas, each constituting
16.4 , 3.5 , 5, 2.2 and 0.7 percentage
respectively. Clinically most of them
presented in Stage III and histologically
most of them belonged to Fuhrman nuclear
grade 2. Histological subtype, tumour
staging, nuclear grading and microvascular
invasion are useful for determining the
prognosis, adjuvant therapy and for followup.