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Secretory carcinoma of breast-a rare case report

Supasakthi S .

Abstract


Secretory carcinoma of breast is a rare histological variant of breast carcinoma with an incidence of 0.15. It is relatively more common in the first three decades of life with median age of 23 years. However it is reported in adults of both sexes. In our institution, a 58 year old female, presented with history of lump in the right breast for 2 years and with pain and ulceration for past six months. Modified radical mastectomy was done. Histopathological examination showed a malignant tumour with microcystic and tubuloalveolar pattern and irregular microlumens containing eosinophilic secretions. Intracytoplasmic and intraluminal secretions showed Periodic Acid Schiff positivity. Immunohistochemistry for Estrogen receptor, Progesterone Receptor and Her 2-neu were negative (triple negative). It was a case of secretory carcinoma of breast. It is a unique, triple negative breast carcinoma ,with indolent clinical behavior, late local recurrences and prolonged survival, even with lymph node metastasis.

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References


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