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A rare case report on Gliosarcoma

Suganya R .

Abstract


Gliosarcoma is a rare malignant glial tumour considered as a variant of Glioblastoma. The clinical presentation, age distribution and treatment modalities are similar to that of glioblastoma. The differentiating features rest on the tumour location, different radiographic appearance, infrequency of EGFR mutation, tendency for extracranial metastasis and poor survival rate.

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References


Stroebe H. Uber Entstehung and Bau der Gehirngliome. Beitr Pathol Anat Allg Pathol. 1895;18: 405-486.

Feigen IH, Gross SW. Sarcoma arising in glioblastoma of the brain. Am J Pathol. 1955;31: 633-653.

Morantz RA, Feigen I, Ransohoff J. Clinical and pathological study of 24 cases of gliosarcoma. J Neurosurg. 1976;45: 398-408.

Salvati M, Caroli E, Raco A, Giangaspero F, Delfini R, Ferrante L. Gliosarcomas: Analysis of 11 cases do two subtypes exist? Neurooncol.2005;74:59-63.

Primary gliosarcoma: key clinical and pathologic distinctions from glioblastoma with implications as a unique oncologic entity J Neurooncol. Feb 2010; 96(3): 313–320.

Reis R, Konu-Lebleblicioglu D, Lopes JM, Kleihues P, Ohgaki H. Genetic profile of gliosarcomas. Am J Pathol. 2000;156: 425–432.

Perry J, Ang LC, Bilbao JM, Muller PJ. Clinicopathologic features of primary and postirradiation cerebral gliosarcoma. Cancer. 1995;75:2910–2918. doi: 10.1002/1097- 0142(19950615) 75:123.0.CO;2-A.

Louis D, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007; 114:97–109. doi: 10.1007/s00401-007-0243-4.

Machuca T, Prevedello DM, Pope LZ, Haratz SS, Araujo JC, Torres LF. Gliosarcoma: report of four cases with immunohistochemical findings. Arq Neuropsiquiatr. 2004; 62:608–612.

Sarkar C, Sharma MC, Sudha K, Gaikwad S, Varma A. A clinicopathological study of 29 cases of gliosarcoma with special reference to two unique variants. Indian J Med Res. 1997;106:229–235


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An Initiative of The Tamil Nadu Dr M.G.R. Medical University