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Pattern of Drug Prescription in the Cardiology Unit of a Tertiary Care Centre

PARVATHY R L LENINRAJENDRAN

Abstract


Abstract INTRODUCTION Rational drug prescription is defined as the use of least number of drugs to obtain the best possible effect in shortest duration and at a reasonable cost. The various unintended outcomes may occur as a result of poor prescribing approach. Cardiovascular diseases are the most common causes of morbidity and mortality throughout the world and number of drugs in single as well as in various  combinations is generally used for long-term management of cardiovascular disorders. AIMS AND OBJECTIVES As prescription based survey is considered as one of the most effective method to evaluate the prescribing attitude of  physicians, this study aimed to focus on the trends in the  prescription of cardiovascular drugs in the Dept of Cardiology in a teritiary care. MATERIALS AND METHODS A descriptive study was undertaken in the Dept of Cardiology during the period from November 2014 to December 2014. 65 patients gave informed consent and were enrolled in the study. Details of prescribed cardiovascular drug(s) like formulation, dose, route of  dministration, frequency, duration, whether the drug was            prescribed using generic name or brand name were recorded in the case record form and were analysed. The collected data was analysed and expressed as percentage. RESULTS It was observed that 52.30 of drug prescriptions were by combination therapy and 47.69 by combination therapy. Among the   combination therapies 44.61 of the patients were prescribed with two drug combinations and 7.69 with three drug combinations none of the fixed dose combinations were  approved by the WHO. The study also showed that all the  prescriptions were by brand names. CONCLUSIONS All the drugs were prescribed by their brand names and most of the drugs were prescribed in combinations and were found to be rational.

 


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References


Arati S, Panchbhai. Rationality of Prescription Writing. Ind J Pharm Educ Res 2013;47(4):7-15.

Shivharae SC, Kunjwani HK, Manikrao AM, Bundra AV. Drug hazards and Rational use of drugs: A Review. J Chem Pharm Res 2010;2(1):106-12.

Andrew PS, Eugene B. Ischaemic heart disease. In Kasper DL (ed). Text book of Harrison’s principle of internal medicine 16th edition. McGraw Hill medical publication division, 2006;1434-44.

Alan E, Francis S. Collins. Cardiovascular disease 2010;349: 60-72.

Prabhakaran D, Yusuf S. Cardiovascular disease in India: Lessons learnt and challenges ahead. Indian J Med Res 2010;132:529-30.

Xavier D, Pais P, Devereaux PJ, Xie C, Prabhakaran D, Reddy KS, Gupta R, et al. Treatment and outcomes of acute coronary syndromes in India (CREATE): a prospective analysis of registry data. Lancet 2008;371:1435–42.

Vamadevan S,Dorairaj P.Coronary heart disease in Indians: Implications of the INTERHEART study.Indian J Med Res 2010; 132(5): 561–66.

Venketashwara B, Swapna Y, Florence S, Santoshi LM, Shweta J, Srinivas N. Drug utilization of antibiotics in surgical ward of a teritiary care hospital. Int J Chem Pharm Sci 2015;6(1):107-13.

Zafar F, Naveed S, Korai OU, Rizvi M, Naqvi GR, Siddiqui S. Drug utilization pattern in cardiovascular diseases: A descriptive study in teritiary care settings in Pakistan J Bioequiv Availab 2015;7(1):59-62.

Rajnandh MG, Ramaswamy C, Khan MI. Pattern of cardiovascular drugs use in outpatients in a teritiary care hospital. Asian J Pharm Clin Res 2012;5(1):109-12.

Muhit A, Rahman O, Raihan SZ, Asaduzzaman M, Akbar MA, Sharmin N, Faroque.

Cardiovascular disease prevalence and prescription patterns at a tertiary level hospital in

Bangladesh. J Pharm Sci 2012 ;2 (3):2012: 80-4.

Devi MAS, Sriram S, Rajalingam B, Anthrapur AR, Varghese RS, Phani VA. Evaluation of the Rationality of Fixed Dose Combinations of Cardiovascular drugs in a Multispecialty Tertiary care hospital in Coimbatore, Tamilnadu, India. Hygeia J D Med 2012;4(1):51-8.

Baskota M, Rao BS, Shakya R. Study on the prescribing pattern of drugs used in heart failure. J Sci Engineering Tech 2006;1:1-6.

Ratnakar UP, Shenoy A, Ullal SD, Shivprakash, Sudhakar, Shastry R, Shoeb A. Prescribing patterns of fixed dose combinations in hypertension, diabetes mellitus and dyslipedimia among patients attending a cardiology clinic in a tertiary care teaching hospital in India. Int J Comprehen Pharm 2011;6:1-3.


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