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Choroid plexus carcinoma

PRIYA PHILIP

Abstract


Abstract Introduction-Choroid plexus carcinoma(CPC) is a malignant neoplasm arising from the epithelium of the choroid plexus of cerebral ventricles. It is a very rare tumour which carries poorer prognosis than choroid plexus papilloma(CPP).Method Case report Result-A seven year old male child presented with history of headache,vomiting and fever. Pre-op MRI showed right occipital horn mass,hippocampus shifted medially with midbrain shift.Surgical resection done.Squash cytology showed choroid plexus neoplasm.Histopathology report revealed choroid plexus carcinoma.Patient received post  operative RT 50.4 Gy .Patient was on regular followup with no recurrence yet.Conclusion Choroid plexus carcinoma has a very poor prognosis when surgery is incomplete. Aggressive surgical resection of the tumor is necessary for survival. Although  radiotherapy and chemotherapy gives promising responses, local control remains the main challenge, and second look surgery has to be considered for patients with incomplete  resection.

 


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References


· Choroid plexus carcinomas in childhood: clinical features and prognostic factors. Berger C1, Thiesse P, Lellouch-Tubiana A, Kalifa C, Pierre-Kahn A, Bouffet E. Department of Pediatric Oncology and Hematology, Hôpital Nord, Saint Etienne, France..

· Purva Gopal, John R. Parker, Robert Debski, and Joseph C. Parker, Jr (2008) Choroid Plexus Carcinoma. Archives of Pathology & Laboratory Medicine: August 2008, Vol. 132, No. 8, pp. 1350- 1354.

· Perez and Brady’s principles and practice of radiation oncology, sixth edition.

· radiopaedia.org/articles/choroid-plexus-carcinoma


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