Cover Image

A STUDY TO MEASURE DAYTIME SLEEPINESS IN HYPOTHYROID PATIENTS

KAVITHA KAVITHA

Abstract


A STUDY TO MEASURE DAYTIME
SLEEPINESS IN HYPOTHYROID PATIENTS
ABSTRACT Sleepiness indicates
an increased physiologic drive to sleep.
Studies have shown that excessive daytime
sleepiness (EDS) is associated with
increase in vehicle clashes. The Epworth
Sleepiness Scale (ESS) provides measure
of a subjects propensity to daytime sleepiness.
AIM 1. To evaluate daytime sleepiness
in newly diagnosed hypothyroid patients
using the Epworth Sleepiness Scale.
2. To compare the ESS score in young
adults, adults and old adults of hypothyroid
patients with euthyroid control subjects. 3.
To evaluate the relationship between snoring
and EDS in terms of ESS questionnaire
responses.MATERIALS AND METHODS
Out of 100 participants, 50 were hypothyroid
patients of both sexes between
the age group of 18 to 50 years and 50
were normal subjects comparable in both
age and gender. Individuals were classified
based on their age into young adults
(18 to 24 years), adults (25 to 44 years)
and old aged adults (45 to 50 years).
The ESS questionnaire contains eight
items that evaluates the chance of a person
napping in different soporific situations.
According to this scale, score of
less than 7 is said to indicate normal
sleep function while a score of more than
10 denotes that the subject suffers from
EDS. Association of snoring and menopause
on EDS was also analysed. Statistical
analysis was carried out and analysed
by means of t-tests for independent
samples and one way ANOVA variation
between the three age groups using statistical
package for social sciences (SPSS
for windows 15).RESULTS Mean ESS
score was significantly higher in all the
age groups in hypothyroid patients. Influence
of snoring and menopause on ESS
score was not found to be statistically significant.
CONCLUSION Hypothyroid patients
suffer from excessive daytime
sleepiness due to sleep disordered
breathing, sleep fragmentation and arousals.
Early diagnosis and management with
hormone replacement therapy, restores
sleep pattern and hence a good quality of
life.


Full Text:

PDF

References


Akerstedt, T. 1988. Sleepiness

as a consequence of shift work.

Sleep 11: 17-34

Roth, T., and T. A.

Roehrs. 1996. Etiologies and sequelae

of excessive daytime

sleepiness. Clin. Ther. 18: 562-

Maycock, G. 1997. Sleepiness

and driving: the experience of U.K.

car drivers. Accid. Anal. Prev. 29:

-462

Johns. M. W. 1994. Sleepiness

in different situations measured by

the Epworth Sleepiness Scale.

Sleep 17: 703-710

Sleep-related breathing disorders

in adults: recommendations

for syndrome definition and measurement

techniques in clinical research:

The Report of an American

Academy of Sleep Medicine

Task Force. Sleep. 1999;22:667-

Johns.M.W.1991 A new method

for measuring

daytime sleepiness :the Epworth

Sleepiness Scale. Sleep ;14:540–545.

Vishesh K. Kapur, Thomas D. Koepsell,

James DeMaine, Richard Hert,

Robert E Sandblom, and Bruce M.

(1998). Association of hypothyroidism

and obstructive sleep apnea Psaty Am

J Respir Crit Care Med;158:1379–1383

Gottlieb DJ, Whitney CW, Bonekat

WH .1999 Relation of sleepiness to

respiratory disturbance index: Am J

Respir Crit Care Med ;159:502–507.

L. Mehran, A. Amouzgar, H. Delshad,

and F. Azizi, The association between

serum TSH concentration and body

mass index in euthyroid subjects; the

role of smoking. Endocrine Research

Center, Research Institute for Endocrine

Sciences, Shahid Beheshti University

of Medical Sciences, Tehran, I.

R. Iran.

Silva JE. (2006). Thermogenic

mechanisms and their hormonal regulation.

Physiol Rev;86:435–64.

Bloch KE. Sleep apnoea syndrome

and morbid snoring. Schweiz Rundsch

Med Prax 1995; 13(24): 736-41.

Viner S, Szalai JP, Hoffstein V.

(1991). Are history and physical examination

a good screening test for sleep

apnea? Ann Intern Med;115:356–9.

David S. C. Hui, MBBS, FCCP, Joseph

K. W. Chan, MBBS, FCCP, Alice

S. S. Ho, MBBS, FCCP, Dominic K. L.

Choy, MBBS, Christopher K. W. Lai,

DM, FCCP and Roland C. C. Leung,

MD

FCCP. Prevalence of Snoring and

Sleep-Disordered Breathing in a Student

Population.

Prevalence of Sleep-disordered

Breathing in Women Effects of Gender

Edward O. Bixler, Alexandros N.

Vgontzas, Hung-Mo Lin, Thomas Ten

Have, Jennifer Rein, Antonio Vela-

Bueno and Anthony Kales Am. J. Respir.

Crit. Care Med. March 1, 2001 vol.

no. 3 608-613Manber R, Armitage

R. Sex, steroids, and sleep: a review.

Sleep 1999; 22 : 540-55.

Vgontzas AN, Papanicolaou DA,

Bixler EO, Hopper K, Lotsikas A, Lin H

-M, Kales A, Chrousos GP. Sleep apnea

and daytime sleepiness and fatigue:

relation to visceral obesity, insulin

resistance, and hypercytokinemia. J

Clin Endocrinol Metabol 2000;85:1151

–1158

Darke, T.S., O'Brien, W.F. and

Tredway, D.R.: Pituitary response to

LHRH in hypothyroid women. Obstet.

Gynecol.56: 488, 1980.


Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.

An Initiative of The Tamil Nadu Dr M.G.R. Medical University