Microbiological profile of pathogenic bacteria in diabetic foot infections in a tertiary care hospital in Tamil Nadu
Abstract
Diabetes mellitus is the most common
medical ailment that majority of the Indian
population is afflicted with. Diabetic foot
infections are one of the most feared complications
of diabetes leading to a high
morbidity rate and one of the leading
causes of hospitalisations and amputation
of limbs. Most of these wounds are polymicrobial
in nature with multi drug resistant
organisms making the management
difficult. For the period of eight months 148
Diabetic wound samples were received
and processed in our laboratory. The
study shows a male predominance of
70.2. The most common age group affected
is between 51 60 years. The commonest
organism causing wound infection
is Staphylococcus aureus followed by the
Enterobacteriaceae group of organisms.
Among the Staphylococcal isolates 43.2
were methicillin resistant S. aureus and
37.5 of the Enterobacteriaceae are extended
spectrum beta lactamase producers.
Fifteen patients (10.1) had more than
one drug resistant organism
Majority of the patients are found to be
empirically treated with amoxicillin clavulanic
acid or cefaperazone sulbactam or
piperacillin tazobactam. A complete microbial
profile with the antibiogram in a
particular hospital will help to guide appropriate
management of diabetic foot infections.
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Dushyant singh gaur, amit varma,
pratima gupta jk science vol. 9 no. 1,
january-march 2007 19 diabetic foot
in Uttaranchal
Vijay viswanathan, sharad pendsey,
arun bal “diabetic foot in india”
medicine update 2005
Ravisekar Gadepalli, Benu Dhawan,
Vishnubhatla Sreenivas , Arti
Kapil, A. C Ammini , Rama
Chaudhry, Diabetes Care 29:1727–
, 2006
Sharma vk, khadka, joshi, sharma r
common pathogens isolated in diabetic
foot infection in bir hospital
kathmandu university medical journal
(2006), vol. 4, no. 3, issue 15, 295-
Mackie TJ, McCartney JE. Practical
medical microbiology. 14th ed.
New York: Churchill Livingstone;
Clinical Laboratory Standards Institute.
Methods for dilution antimicrobial
susceptibility tests for bacteria
that grow aerobically. Approved
standard, 6th ed. CLSI document M7
-A6. Wayne, PA: CLSI; 2005.
Clinical Laboratory Standards Institute.
Performance standards for antimicrobial
disk susceptibility tests.
Approved standard, 9th ed. CLSI
document M2-A9. Wayne, PA: CLSI;
CLSI Performance testing for Antimicrobial
susceptibility testing; twenty first
informational supplemnt. M 100 S21 Vol
no 1
Frykberg RG, Armstrong DG, Giurini J,
Edwards A, Kravette M, Kravitz S, et al.
Diabetic foot disorders: a clinical practice
guideline. American College of Foot and
Ankle Surgeons. J Foot Ankle Surg
; 39: S1-60.
Sharma VK1, Khadka PB2, Joshi A3,
Sharma R4 Common pathogens isolated
in diabetic foot infection in Bir Hospital
Kathmandu University Medical Journal
(2006), Vol. 4, No. 3, Issue 15, 295-301
Dushyant Singh Gaur, Amit Varma,
Pratima Gupta Diabetic Foot in
Uttaranchal Vol. 9 No. 1, January-March
Sivaraman Umadevi, Shailesh
Kumar, Noyal Mariya Joseph, Joshy M
Easow, G Kandhakumari, Sreenivasan
Srirangaraj, Sruthi Raj, Selvaraj
Stephen. Microbiological study of diabetic
foot infections Indian Journal of
Medical specialities 2011;2(1):12-17
Anandi C, Alaguraja D, Natarajan V,
Ramanathan M, Subramaniam CS, Thulasiram
M, et al. Bacteriology of diabetic
foot lesions. Indian J Med Microbiol
;22: 175-8.
Shankar EM, Mohan V, Premalatha G,
Srinivasan RS, Usha AR. Bacterial etiology
of diabetic foot infections in South
India. Eur J Intern Med 2005; 16: 567-70.
Mohammad Zubair, Abida Malik,
Jamal Ahmad Clinico-bacteriology
and risk factors for the diabetic foot
infection with multidrug resistant microorganisms
in north India Biology
and Medicine, Vol 2 (4): 22-34, 2010
Deeba Bashir, Manzoor Ahmad
Thokar, Bashir Ahmad Fomda1, Gulnaz
Bashir, Danish Zahoor, Shabir
Ahmad and Abubaker S. Toboli. Detection
of metallo-beta-lactamase
(MBL) producing Pseudomonas
aeruginosa at a tertiary care hospital
in Kashmir African Journal of Microbiology
Research Vol. 5(2) pp. 164-
, 18 January, 2011
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