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DETECTION OF ESBL AND MBL PRODUCING PSEUDOMONAS AERUGINOSA IN TIRUNELVELI MEDICAL COLLEGE HOSPITAL

JEYABHARATHI JK JKATHIRVELAN

Abstract


AIM The present study was done to detect  Extended spectrum beta lactamase and     metallo-beta-lactamase producing isolates of Pseudomonas aeruginosa from varaious clinical samples from patients  admitted in Tirunelveli medical college hospital. MATERIAL AND METHODS In this study we studied the prevalence of ESBL and MBL among 112 Pseudomonas aeruginosa    isolates, following standard methods of isolation and   identification of these bacteria from clinical materials   RESULTS Out of 112 isolates of Pseudomonas aeruginosa, 32 were producing Extended spectrum beta lactamase    enzyme producing isolates, 11 isolates were resistance to Imipenem . Of the 11 imipinem resistant isolates, 7 were  metallo -beta-lactamase enzyme producing     isolates. CONCLUSION The present study underlines the unique problem that the presence of ESBL has led to the           widespread use of Imipenem which in turn led to the           emergence of MBLs .Infection caused by MBL                           (metallo-beta-lactamase) positive isolates of Pseudomonas aeruginosa is important to identify because it poses not only therapeutic problem due to broad spectrum drug resistance, but also a serious concern for infection control.

 


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