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A Study of Serum Ghrelin Levels in Obese Individuals

Dr. K. Meenakumari .

Abstract


Background Obesity is a common nutritional problem faced by world today. The common causes of obesity are  sedentary life, improper eating habits, stress, smoking,   alcoholism apart from genetically determined factors. Obesity is a proved risk factor in atherosclerosis, CHD, stroke, sleep            apnoea, and numerous malignancies. Ghrelin is a hunger   hormone and its levels vary physiologically with appetite and satiety. Aim To study and analyse the serum level of ghrelin levels in obese individuals. Methods The study includes   randomly selected (equal male and female) 30 controls and 30 obese individuals. Age group of the individuals lie between  20- 50 years. Individuals with epilepsy, diabetic, endocrine  dysfunction, known cardiovascular or GI problems were    excluded from the study. Results The results showed no  significant sex difference in the serum ghrelin levels (p 0.05). Serum ghrelin levels are reduced significantly with p value 0.000 in obese. Conclusion Serum Ghrelin levels are significantly  reduced in obese individuals irrespective of sex.

 


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References


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Circulating Ghrelin Levels Are Decreased in Human Obesity Matthias Tschöp, Christian Weyer, P. Antonio Tataranni, Viswanath Devanarayan, Eric Ravussin and Mark L. Heiman.


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An Initiative of The Tamil Nadu Dr M.G.R. Medical University