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Dapsone hypersensitivity with renal involvement - An extremely rare presentation

MEERA DEVI A

Abstract


Dapsone is widely used in the treatment of leprosy and variety of neutrophilic dermatoses. Dapsone   Hypersensitivity Syndrome (DHS) is an idiosyncratic reaction to dapsone and presents with a potentially fatal triad of fever, skin eruption and internal organ involvement.1 . DHS can occur within several days to as late as 6 months after initial exposure to the drug. We report an adolescent male patient who   developed Dapsone Hypersensitivity reaction with acute   tubulointerstitial nephritis after short course of Dapsone for nodulocystic acne.

 


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