A STUDY ON BACTERIAL PROFILE AND ANTIBIOTIC SUSCEPTIBILITY PATTERN IN POST SURGICAL WOUND INFECTION IN A TERTIARY CARE CENTRE
Abstract
OBJECTIVE To study the bacterial profile
and antibiotic susceptibility pattern in post
surgical wound infections.MATERIALS
AND METHODS This study was done in
patients with post surgical wound infections.
Pus samples were collected from
wound discharge using sterile swab and
processed by Gram staining and culturing
on to appropriate plates.Antibiotic susceptibility
testing was done by Disc diffusion
method (Kirby Bauer method) on Mueller
Hinton Agar . RESULTS Out of 50 samples,
54 organisms were isolated. E.coli
was the predominant isolate( 29.6 percentage),
followed by Pseudomonas aeruginosa
( 22.2 percentage) . E.coli was 31.3
percentage sensitive to Ceftazidime, 43.8
percentage sensitive to Ofloxacin, 93.8
percentage sensitive to Amikacin and were
100 p-ercentage sensitive to Cefoperazone
sulbactum and Imipenem . Pseudomonas
aeruginosa was 16.7 percentage
sensitive to Ceftazidime Ofloxacin,41.7
percentage sensitive to Amikacin,91.7 percentage
sensitive to
Cefoperazone sulbactum and 100 percentage
sensitive to Imipenem.Klebsiella
pneumoniae was 66.7 percentage sensitive
to Amikacin and Ofloxacin but only
16.7 percentage sensitive to Ceftazidime.
It was 100 percentage sensitive
to Cefoperazone sulbactam and
Imipenem.Staphylococcus aureus was
100 percentage sensitive to Amikacin and
62.5 percentage sensitive to Erythromycin
and Cephalexin and 12.5 percentage sensitive
to Ciprofloxacin.Staphylococcus epidermidis
was 50 percentage sensitive to
Amikacin ,Cotrimoxazole,Ciprofloxacin
and Tetracycline.Only one Enterococcus
faecalis was isolated and it was sensitive
to Amikacin, Ciprofloxacin and Penicillin.
CONCLUSION High resistance rates
has been observed for Cephalosporins
and Fluoroquinolones among the Gram
negative bacilli in post surgical wound infections.
Amikacin ,Cefoperazone sulbactum
and Imipenem were found effective in
these organisms and they will be effective
in formulating the prophylactic therapy for
prevention of post surgical wound infection.
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