AN AUDIT OF IMMEDIATE ADVERSE EFFECTS OF BLOOD TRANSFUSION REPORTED IN A TERTIARY CARE HOSPITAL

Abstract

Data from specific registers of the Medical
College Hospital Blood Bank from 2008 to
2010 was collected to audit the occurrence
of immediate transfusion reactions (ITR)
and their distribution across the various
blood products that were issued. The average
occurrence of ITR during the study
period was 2.3 per 1000 issues. Of the
100 ITR that occurred during the study period
63 were mild allergic reactions followed
by febrile non-haemolytic transfusion
reactions (FNHTR). Packed RBCs
were responsible for 91 percent of the
FNHTR while allergic reaction was noted
with all the blood products. All the three
anaphylactoid reactions were observed
with the use of fresh frozen plasma. The
use of lab side leukocyte filters would play
a significant role in bringing down the incidence
of FNHTR associated with the use
of Packed RBCs.