Cover Image

MULTIFOCAL INFLAMMATORY PSEUDOTUMOUR OF LIVER (IPT) MIMICING METASTASIS -IMPORTANCE OF BIOPSY FOR SPACE OCCUPYING LESIONS IN LIVER

GAURAV CHAWLA

Abstract


Multifocal inflammatory pseudotumour of
liver(IPT) is an uncommon tumor of liver.
Exact etio-pathogenesis of this entity is
yet to be elucidated. It can mimic clinically
and radiologically with metastasis,
hepatocellular carcinoma or hepatobiliary
tuberculosis. It can even present as pyrexia
of unknown origin. A 48 year old
gentleman presented with fever and
weight loss. He had multiple space occupying
lesions in the liver. Ultrasound
guided liver biopsy was suggestive of inflammatory
pseudotumour of liver. He
was treated conservatively. In present
case diagnosis of liver IPT was carried
out by fine needle liver biopsy. Indeed
we believe that if clinical manifestations,
imaging studies, level of tumour markers
and results of histopathology specimens
as obtained by fine needle biopsy are
taken into account, accurate diagnosis of
liver IPT can be made and surgery can
be avoided.
Keyword :multifocal pseudotumour of
liver, fine needle biopsy, fever of unknown
origin, India


Full Text:

PDF

References


Pack GT, Baker HW: Total right

hepatic lobectomy; report of a

case. Ann Surg 1953, 138(2):253-

Chong A, Jeong SY, Min JJ. Inflammatory

pseudotumours resembling

multiple hepatic metastases

and their complete regression, as

revealed by 18F-FDG PET/CT. Eur

J Nucl Med Mol Imaging

;36:1199-200

Brage-Varela A, Estevez-

Boullosa P, Pombo-Otero J,

Blanco-Rodriguez M, Lago-Novoa

M, Arnal-Monreal F.Multifocal he

Sari A, Tunakan M, Unsal B, Ekinci N,

Rezanko T, Elcin F, et al. Inflammatory

pseudotumor of the liver diagnosed by

needle biopsy: Report of three cases

(one with neuroendocrine tumor of the

rectum and lung). Turk J Gastroenterol

;21:308-12.

Kawaguchi T, Mochizuki K, Kizu T, Miyazaki

M,Yakushijin T, Tsutsui S, et al.

Inflammatory pseudotumorof the liver and

spleen diagnosed by percutaneous needlebiopsy.

World J Gastroenterol

;18:90-5.

Amir Hossein Sarrami, Mohammad Mehdi

Baradaran-Mahdavi, Mohsen Meidani

Precise recognition of liver inflammatory

pseudotumor may prevent an unnecessary

surgery. Int J Prev Med 2012;3:432-

Ueda J, Yoshida H, Taniai N, Onda M,

Hayashi H, Tajiri T. Inflammatory pseudotumor

in the liver associated with intrahepatic

bile duct stones mimicking malignancy.

J Nihon Med Sch 2009;76:154-5

Goldsmith PJ, Loganathan A, Jacob M,

Ahmad N, Toogood GJ, Lodge JPA

Prasad KR: Inflammatory pseudotumours

of the liver: a spectrum of presentation

and management options. Eur J Surg

Oncol 2009,35(12):1295-1298.

Lupovitch A, Chen R, Mishra S: Inflammatory

pseudotumour of the liver.Report

of the fine needle aspiration cytologic

findings in a case initiallymisdiagnosed

as malignant. Acta Cytol 1989, 33(2):259-

Toda K, Yasuda I, Nishigaki Y, Enya

M, Yamada T, Nagura K, et

al:Inflammatory pseudotumour of the liver

with primary sclerosing cholangitis. J

Gastroenterol 2000, 35:304-309.

Sasahira N, Kawabe T, Nakamura

A, Shimura K, Shimura H, Itobayashi

E,et al: Inflammatory pseudotumour

of the liver and peripheral

eosinophilia in autoimmune pancreatitis.

World J Gastroenterol

,11:922-925.

Hirano K, Shiratori Y, Komatsu Y,

Yamamoto N, Sasahira N, Toda N,

et al:Involvement of the biliary system

in autoimmune pancreatitis: A

followup study. Clin Gastroenterol

Hepatol 2003, 1:453 564

Papachristou GI, Wu T, Marsh

W, Plevy SE: Inflammatory pseudotumour

ofthe liver associated with

Crohn’s disease. J Clin Gastroenterol

,38:818-822.

Hosokawa A, Takahashi H,

Akaike J, Okuda H, Murakami R,

Kawahito Y, et al:A case of

Sjögren’s syndrome associated with

inflammatory pseudotumour of the

liver. Nihon Rinsho Meneki Gakkai

Kaishi 1998,21:226-233.

Fickert P, Zollner G, Fuchsbichler

A, Stumptner C, Weiglein AH, Lammert

F,et al: Ursodeoxycholic acid

aggravates bile infarcts in bile ductligated

and Mdr2 knockout mice via

disruption of cholangioles. Gastroenterology

, 123:1238-1251.

Faraj W, Ajouz H, Mukherji D,

Kealy G, Shamseddine A, Khalife M.

Inflammatory pseudo-tumor of the

liver:A rare pathological entity. World

J Surg Oncol 2011;9:5.

Ogawa T, Yokoi H, Kawarada Y.

A case of inflammatory pseudotumor

of the liver causing

elevated serum CA19-9 levels. Am J

Gastroenterol 1998;93:2551-5.

Tsou YK, Lin CJ, Liu NJ, Lin CC, Lin

CH, Lin SM. Inflammatory pseudotumor

of the liver: Report of eight cases, including

three unusual cases, and a literature

review. J Gastroenterol Hepatol

;22:2143-7.

Deng FT, Li YX, Ye L, Tong L, Yang

XP, Chai XQ. Hilar inflammatory pseudotumor

mimicking hilar cholangiocarcinoma.

Hepatobiliary Pancreat Dis Int

;9:219-21.


Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.

An initiative of The Tamil Nadu Dr M.G.R. Medical University